Megadose Creatine: Fix Insulin, Melt Fat & Rewire Your Brain [Dr Candow] @ThePrimal.Podcast
Megadose Creatine: Fix Insulin, Melt Fat & Rewire Your Brain [Dr Candow]  @ThePrimal.Podcast
Uploaded November 2025 | Updated September 2026, 1 day ago
Dr. Darren Candow and Rina Ahluwalia delve into the multifaceted benefits of creatine supplementation. They explore its importance for both men and women, optimal dosing strategies [why 5 grams is not enough], and the various health benefits associated with creatine, including muscle strength, brain health, and potential applications in conditions like depression and Alzheimer's. The conversation also addresses common myths surrounding creatine, such as its effects on kidney health and hair loss, while emphasizing the significance of exercise in maximizing its benefits. Overall, this dialogue serves as an informative guide for anyone considering creatine as part of their health and fitness regimen.

Takeaways
* Creatine is conditionally essential for optimal health.
* Women benefit significantly from creatine supplementation.
* The optimal dose for strength gains is around 5 grams per day.
* Creatine is a natural compound produced in the body.
* Red meat and fatty fish are the best dietary sources of creatine.
* Caffeine may enhance performance more than creatine.
* Creatine improves ATP resynthesis, aiding muscle performance.
* Creatine can aid recovery in endurance athletes.
* Creatine may help with fat loss when combined with exercise.
* Creatine is safe for long-term use and has no adverse effects on kidneys.

Timestamps
00:00 Understanding Creatine: Dietary Sources and Supplementation
08:50 What is Creatine?
11:28 Creatine vs. Caffeine
15:40 Creatine and Strength: Mechanisms and Benefits
26:04 Creatine and Cognitive Benefits
29:22 Creatine's Role in Mental Health
32:07 Creatine and Sleep Deprivation
34:11 The Stigma Around Creatine
35:41 Creatine for Traumatic Brain Injury
37:20 Creatine Dosage for Brain Health
39:20 Creatine's Potential in Cancer Treatment
40:48 Creatine and Insulin Resistance
41:50 Creatine's Impact on Bone Health
44:59 The Importance of Bone Health
47:21 Creatine and Cardiovascular Benefits
48:14 Choosing the Right Creatine
49:53 Loading Phase and Dosing Strategies
53:35 Addressing Myths About Creatine
56:52 Creatine Use in Children and Pregnancy
59:48 Final Thoughts on Creatine

Darren Candow, PhD
X: https://x.com/darrencandow
Instagram: instagram.com/dr.darrencandow

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About Rina - The Primal Podcast

Rina Ahluwalia breaks down the truth about getting healthy and losing weight— based on science. On her health podcast, she interviews top doctors and experts about the power of low-carb and ketogenic diets, the carnivore diet, and intermittent fasting.

As the founder of GoCarnivore.com, Rina is a recognized leader in the health space, helping people take control of their weight and well-being through real, nutrient-dense food.

Want to jumpstart your health? Join the free 90-day challenge at GoCarnivore.com or visit ThePrimal.com for more!
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Megadose Creatine: Fix Insulin, Melt Fat & Rewire Your Brain [Dr Candow]

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