Uploaded May 2026 | Updated September 2026, 2 weeks ago
If your skin has gotten drier, thinner, or less plump since your 40s, this isn't your skincare routine failing you. It's your hormones — and understanding what's actually happening is the first step to doing something about it.
Triple board-certified dermatologist @dr.mamina breaks down exactly what estrogen loss does to skin in perimenopause: the drop in hyaluronic acid, the loss of collagen thickness, the crepe texture on arms and under eyes. She also explains glycation — the way blood sugar quietly accelerates collagen breakdown — and defines melasma: what drives it, who gets it, and why hormonal shifts are almost always involved.
This is the skin science most women in midlife were never taught.
Watch the full episode: youtu.be/EqnYY8X9dho
If your skin has gotten drier, thinner, or less plump since your 40s, this isn't your skincare routine failing you. It's your hormones — and understanding what's actually happening is the first step to doing something about it.
Triple board-certified dermatologist @dr.mamina breaks down exactly what estrogen loss does to skin in perimenopause: the drop in hyaluronic acid, the loss of collagen thickness, the crepe texture on arms and under eyes. She also explains glycation — the way blood sugar quietly accelerates collagen breakdown — and defines melasma: what drives it, who gets it, and why hormonal shifts are almost always involved.
This is the skin science most women in midlife were never taught.
Watch the full episode: youtu.be/EqnYY8X9dho










