The Proof with Simon Hill | Revolutionizing Brain Health: Genetics, Lipid Science, and Cutting-Edge Dementia Prevention @TheProofWithSimonHill | Uploaded September 2024 | Updated October 2024, 3 hours ago.
What does cholesterol have to do with dementia? Join me in Episode #333 as I sit down with Dr Kellyann Niotis and Dr Thomas Dayspring to explore how cholesterol metabolism impacts brain health and what you can do to reduce your risk of cognitive decline. From cutting-edge insights into cholesterol’s role in neurodegenerative diseases to key risk factors for dementia, this episode provides practical tips to help you protect your brain for years to come.
👇 Visit The Proof website for the full show notes and supporting studies. 👇 theproof.com/podcast
Dr Kellyann Niotis is a preventive neurologist and the Director of Parkinson’s Disease & Lewy Body Dementia Prevention Research at the Institute for Neurodegenerative Diseases Florida. She leads the preventive neurology program at Early Medical and is the first fellowship-trained preventive neurologist in the U.S. Dr Thomas Dayspring is a renowned clinical lipidologist, Fellow of the American College of Physicians, and expert in cholesterol metabolism with decades of experience. Together, they bring extensive knowledge and understanding of how cholesterol and lifestyle factors impact brain and cardiovascular health.
Connect with Dr Kellyann Niotis:
- Website: drkellyannniotis.com
- Resources and research: ind.org
Connect with Dr Thomas Dayspring:
- Twitter/X: https://x.com/Drlipid
- LinkedIn: linkedin.com/in/thomas-dayspring-md-facp-fnla-3aaa876
- Past episodes: theproof.com/tag/thomas-dayspring
Highlights:
00:00 Intro
07:53 Cardiology Meets Neurology: Understanding the Connection
13:26 Dementia and Neurodegenerative Diseases: A Comprehensive Overview
21:36 Recognizing Early Dementia Signs and Risk Factors
32:36 Lipoproteins and Brain Health: The Crucial Link
44:20 ApoB vs ApoE: Comparing Apoprotein Functions in Neurological Health
01:01:13 APOE4 Carriers: Potential Therapeutic Approaches
01:04:10 ApoA1 and HDL: Their Role in Dementia Prevention
01:14:15 Genetic Testing for Dementia: Understanding APOE4 Implications
01:19:51 APOE4 Gene: Impact on Dementia Risk and Brain Health
01:22:53 Desmosterol's Role in Maintaining Brain Health
01:36:25 LDL Cholesterol: A Key Factor in Dementia Risk Assessment
01:43:27 APOE4: Comparing Single vs. Double Copy Risk Factors
01:48:13 Omega-3 Fatty Acids: Essential Nutrients for Brain Health
01:58:43 LDL Cholesterol Levels: Assessing Low vs. High Risk for Dementia
02:01:57 Key Takeaways: Preventive Neurology and Future Research Directions
If you have any additional questions you would like answered in the future, let me know in the comments.
Enjoy, friends.
Simon
This episode is brought to you by:
38TERA
Consider 38TERA's DMN-01 prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Head to 38tera.com and use code THEPROOF for a discount at checkout.
Eimele
Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Head to eimele.com and use code SIMON at checkout for 10% off your first order.
WHOOP
Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon
Shopify
Shopify, the world's leading e-commerce platform, helps you turn browsers into buyers with the internet’s best-converting check out–up to 36% better compared to other leading e-commerce platforms. To boost your conversion rate, and grow your business, sign up for a one-dollar-per-month trial period at shopify.com/proof
Birch
Sleep deeply and wake up refreshed with a Birch Natural Mattress, combining premium natural materials with unbeatable comfort. Rest easy with a 100-night trial and 25-year warranty. Get 25% off all mattresses and 2 free pillows at birchliving.com/simonhill
Want to support the show?
The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends. You can also show your support by leaving a review on the Apple Podcast app and/or sharing your favourite episodes with your friends and family.
Simon Hill, MSc, BSc (Hons)
Creator of theproof.com and host of theproof.com/podcast
Author of theproof.com/book
Connect with me on Instagram instagram.com/theproof/, Twitter mobile.twitter.com/theproof, and Facebook facebook.com/theproofwithsimonhill
Nourish your gut with my Plant-Based Ferments Guide theproof.com/ferments
Download my complimentary Two-Week Meal Plan plantproof.com/mealplan and high protein Plant Performance recipe book theproof.com/performance
What does cholesterol have to do with dementia? Join me in Episode #333 as I sit down with Dr Kellyann Niotis and Dr Thomas Dayspring to explore how cholesterol metabolism impacts brain health and what you can do to reduce your risk of cognitive decline. From cutting-edge insights into cholesterol’s role in neurodegenerative diseases to key risk factors for dementia, this episode provides practical tips to help you protect your brain for years to come.
👇 Visit The Proof website for the full show notes and supporting studies. 👇 theproof.com/podcast
Dr Kellyann Niotis is a preventive neurologist and the Director of Parkinson’s Disease & Lewy Body Dementia Prevention Research at the Institute for Neurodegenerative Diseases Florida. She leads the preventive neurology program at Early Medical and is the first fellowship-trained preventive neurologist in the U.S. Dr Thomas Dayspring is a renowned clinical lipidologist, Fellow of the American College of Physicians, and expert in cholesterol metabolism with decades of experience. Together, they bring extensive knowledge and understanding of how cholesterol and lifestyle factors impact brain and cardiovascular health.
Connect with Dr Kellyann Niotis:
- Website: drkellyannniotis.com
- Resources and research: ind.org
Connect with Dr Thomas Dayspring:
- Twitter/X: https://x.com/Drlipid
- LinkedIn: linkedin.com/in/thomas-dayspring-md-facp-fnla-3aaa876
- Past episodes: theproof.com/tag/thomas-dayspring
Highlights:
00:00 Intro
07:53 Cardiology Meets Neurology: Understanding the Connection
13:26 Dementia and Neurodegenerative Diseases: A Comprehensive Overview
21:36 Recognizing Early Dementia Signs and Risk Factors
32:36 Lipoproteins and Brain Health: The Crucial Link
44:20 ApoB vs ApoE: Comparing Apoprotein Functions in Neurological Health
01:01:13 APOE4 Carriers: Potential Therapeutic Approaches
01:04:10 ApoA1 and HDL: Their Role in Dementia Prevention
01:14:15 Genetic Testing for Dementia: Understanding APOE4 Implications
01:19:51 APOE4 Gene: Impact on Dementia Risk and Brain Health
01:22:53 Desmosterol's Role in Maintaining Brain Health
01:36:25 LDL Cholesterol: A Key Factor in Dementia Risk Assessment
01:43:27 APOE4: Comparing Single vs. Double Copy Risk Factors
01:48:13 Omega-3 Fatty Acids: Essential Nutrients for Brain Health
01:58:43 LDL Cholesterol Levels: Assessing Low vs. High Risk for Dementia
02:01:57 Key Takeaways: Preventive Neurology and Future Research Directions
If you have any additional questions you would like answered in the future, let me know in the comments.
Enjoy, friends.
Simon
This episode is brought to you by:
38TERA
Consider 38TERA's DMN-01 prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Head to 38tera.com and use code THEPROOF for a discount at checkout.
Eimele
Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Head to eimele.com and use code SIMON at checkout for 10% off your first order.
WHOOP
Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon
Shopify
Shopify, the world's leading e-commerce platform, helps you turn browsers into buyers with the internet’s best-converting check out–up to 36% better compared to other leading e-commerce platforms. To boost your conversion rate, and grow your business, sign up for a one-dollar-per-month trial period at shopify.com/proof
Birch
Sleep deeply and wake up refreshed with a Birch Natural Mattress, combining premium natural materials with unbeatable comfort. Rest easy with a 100-night trial and 25-year warranty. Get 25% off all mattresses and 2 free pillows at birchliving.com/simonhill
Want to support the show?
The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends. You can also show your support by leaving a review on the Apple Podcast app and/or sharing your favourite episodes with your friends and family.
Simon Hill, MSc, BSc (Hons)
Creator of theproof.com and host of theproof.com/podcast
Author of theproof.com/book
Connect with me on Instagram instagram.com/theproof/, Twitter mobile.twitter.com/theproof, and Facebook facebook.com/theproofwithsimonhill
Nourish your gut with my Plant-Based Ferments Guide theproof.com/ferments
Download my complimentary Two-Week Meal Plan plantproof.com/mealplan and high protein Plant Performance recipe book theproof.com/performance
