Uploaded February 2023 | Updated September 2026, 3 weeks ago
Rats are also useful for aging research and for cooking ratatouille. But in all seriousness, take a look at this recent headline article - “We have the oldest living female Sprague Dawley rat,” said Dr Harold Katcher, a former biology professor at the University of Maryland, now chief scientific officer at Yuvan Research, a California-based startup.
So, Rejuvenation & rats. That’s what we’re talking about today, and how this rat has apparently become the longest living rat for its species following concentrated plasma injections from young blood plasma, and what this could mean for human therapeutics, along my perspectives. But, before we get there we must go back, back to the late 1950s and early 1960...to a time when The Sheekey Science Show did not exist, but when researchers, such as Clive McKay did, and these researchers were conducting a procedure called heterochronic parabiosis.
Find me on Twitter - twitter.com/EleanorSheekey
Support the channel
through PayPal - paypal.me/sheekeyscience?country.x=GB&locale.x=en_GB
through Patreon - patreon.com/TheSheekeyScienceShow
Conference i mentioned - curing-aging.com
TIMESTAMPS:
Intro - 00:00
Plasma & rejuvenation - 00:45
E5 Rat plasma experiments - 04:00
Discussion - 09:44
References:
theguardian.com/science/2023/feb/08/anti-ageing-scientists-extend-lifespan-of-oldest-living-lab-rat
Patent - https://patentscope.wipo.int/search/en/detail.jsf?docId=WO2022150818&_cid=P12-LDLTHI-23678-1
Reversing age: dual species measurement of epigenetic age with a single clock. Steve Horvath bioRxiv 2020.05.07.082917; doi: doi.org/10.1101/2020.05.07.082917
Villeda, S., Plambeck, K., Middeldorp, J. et al. Young blood reverses age-related impairments in cognitive function and synaptic plasticity in mice. Nat Med 20, 659–663 (2014). doi.org/10.1038/nm.3569
i took the video interview clips from @yuvanresearch2749
Please note that The Sheekey Science Show is distinct from Eleanor Sheekey's teaching and research roles at the University of Cambridge. The information provided in this show is not medical advice, nor should it be taken or applied as a replacement for medical advice. The Sheekey Science Show and guests assume no liability for the application of the information discussed.
Icons in intro; "freepik.com/free-photos-vectors/background"Background vector created by freepik - freepik.com
Rats are also useful for aging research and for cooking ratatouille. But in all seriousness, take a look at this recent headline article - “We have the oldest living female Sprague Dawley rat,” said Dr Harold Katcher, a former biology professor at the University of Maryland, now chief scientific officer at Yuvan Research, a California-based startup.
So, Rejuvenation & rats. That’s what we’re talking about today, and how this rat has apparently become the longest living rat for its species following concentrated plasma injections from young blood plasma, and what this could mean for human therapeutics, along my perspectives. But, before we get there we must go back, back to the late 1950s and early 1960...to a time when The Sheekey Science Show did not exist, but when researchers, such as Clive McKay did, and these researchers were conducting a procedure called heterochronic parabiosis.
Find me on Twitter - twitter.com/EleanorSheekey
Support the channel
through PayPal - paypal.me/sheekeyscience?country.x=GB&locale.x=en_GB
through Patreon - patreon.com/TheSheekeyScienceShow
Conference i mentioned - curing-aging.com
TIMESTAMPS:
Intro - 00:00
Plasma & rejuvenation - 00:45
E5 Rat plasma experiments - 04:00
Discussion - 09:44
References:
theguardian.com/science/2023/feb/08/anti-ageing-scientists-extend-lifespan-of-oldest-living-lab-rat
Patent - https://patentscope.wipo.int/search/en/detail.jsf?docId=WO2022150818&_cid=P12-LDLTHI-23678-1
Reversing age: dual species measurement of epigenetic age with a single clock. Steve Horvath bioRxiv 2020.05.07.082917; doi: doi.org/10.1101/2020.05.07.082917
Villeda, S., Plambeck, K., Middeldorp, J. et al. Young blood reverses age-related impairments in cognitive function and synaptic plasticity in mice. Nat Med 20, 659–663 (2014). doi.org/10.1038/nm.3569
i took the video interview clips from @yuvanresearch2749
Please note that The Sheekey Science Show is distinct from Eleanor Sheekey's teaching and research roles at the University of Cambridge. The information provided in this show is not medical advice, nor should it be taken or applied as a replacement for medical advice. The Sheekey Science Show and guests assume no liability for the application of the information discussed.
Icons in intro; "freepik.com/free-photos-vectors/background"Background vector created by freepik - freepik.com
