Uploaded January 2022 | Updated September 2026, 3 weeks ago
You may have heard a lot of talk recently about cellular reprogramming, rejuvenation or even "rejuvenation programming", but what does that all mean and what are the 3 main strategies that several researchers and companies (maybe Altos Labs) will be further investigating?
Well i discuss in this video.
Find me on Twitter - twitter.com/EleanorSheekey
Support the channel
through PayPal - paypal.me/sheekeyscience?country.x=GB&locale.x=en_GB
through Patreon - patreon.com/TheSheekeyScienceShow
TIMESTAMPS:
Intro - 00:00
What is rejuvenation? - 00:40
Strategy 1 - Heterochronic transplants - 01:45
Strategy 2 - Cellular Reprogramming - 04:35
Strategy 3 - Endogenous/Natural rejuvenation - 06:45
References:
Zhang, B., Trapp, A., Kerepesi, C., & Gladyshev, V. N. (2022). Emerging rejuvenation strategies—Reducing the biological age. Aging Cell, 21, e13538. doi.org/10.1111/acel.13538
Abad, M., Mosteiro, L., Pantoja, C. et al. Reprogramming in vivo produces teratomas and iPS cells with totipotency features. Nature 502, 340–345 (2013). doi.org/10.1038/nature12586
Reversing age: dual species measurement of epigenetic age with a single clock - biorxiv.org/content/10.1101/2020.05.07.082917v1
Please note that The Sheekey Science Show is distinct from Eleanor Sheekey's teaching and research roles at the University of Cambridge. The information provided in this show is not medical advice, nor should it be taken or applied as a replacement for medical advice. The Sheekey Science Show and guests assume no liability for the application of the information discussed.
Icons in intro; "freepik.com/free-photos-vectors/background"Background vector created by freepik - freepik.com
You may have heard a lot of talk recently about cellular reprogramming, rejuvenation or even "rejuvenation programming", but what does that all mean and what are the 3 main strategies that several researchers and companies (maybe Altos Labs) will be further investigating?
Well i discuss in this video.
Find me on Twitter - twitter.com/EleanorSheekey
Support the channel
through PayPal - paypal.me/sheekeyscience?country.x=GB&locale.x=en_GB
through Patreon - patreon.com/TheSheekeyScienceShow
TIMESTAMPS:
Intro - 00:00
What is rejuvenation? - 00:40
Strategy 1 - Heterochronic transplants - 01:45
Strategy 2 - Cellular Reprogramming - 04:35
Strategy 3 - Endogenous/Natural rejuvenation - 06:45
References:
Zhang, B., Trapp, A., Kerepesi, C., & Gladyshev, V. N. (2022). Emerging rejuvenation strategies—Reducing the biological age. Aging Cell, 21, e13538. doi.org/10.1111/acel.13538
Abad, M., Mosteiro, L., Pantoja, C. et al. Reprogramming in vivo produces teratomas and iPS cells with totipotency features. Nature 502, 340–345 (2013). doi.org/10.1038/nature12586
Reversing age: dual species measurement of epigenetic age with a single clock - biorxiv.org/content/10.1101/2020.05.07.082917v1
Please note that The Sheekey Science Show is distinct from Eleanor Sheekey's teaching and research roles at the University of Cambridge. The information provided in this show is not medical advice, nor should it be taken or applied as a replacement for medical advice. The Sheekey Science Show and guests assume no liability for the application of the information discussed.
Icons in intro; "freepik.com/free-photos-vectors/background"Background vector created by freepik - freepik.com
