Uploaded December 2020 | Updated September 2026, 3 weeks ago
There are more than 200 different geroprotective compounds. Some of these are already available as supplements, some are in clinical trials and some have FDA approval. Which are my top 5 that I think i most promising in terms of their anti-aging effects (so focusing more on healthspan than lifespan). And note the use of "promising" - there is still much work to be done to better investigate the long-term safety, dose and timings of different supplements which you should always bear in mind.
Anyway, I made this video more for a bit of fun and to make a longer summary video to pull ideas together from multiple previous videos with some new info too! So hope you like it!
Do my top 5 match yours?
#aging #anti-aging #supplements #nmn #akg
TIMESTAMPS:
Intro & useful resources - 00:00
Pick #1 - 03:10
Pick #2 - 06:14
Pick #3 - 08:52
Pick #4 - 11:24
Pick #5 - 12:54
Round-up - 15:28
Bonus #1 - 16:10
Bonus #2 - 16:25
References;
Check out @LifespanIO rejuvenation road map;
lifespan.io/road-maps/the-rejuvenation-roadmap
Nature comment - nature.com/articles/d41586-018-01668-0#:~:text=A%20class%20of%20drugs%20called,muscles%2C%20immune%20system%20and%20more.
AKG news - buckinstitute.org/news/a-metabolite-produced-by-the-body-increases-lifespan-and-dramatically-compresses-late-life-morbidity-in-mice
TAME trial - afar.org/tame-trial
Table I showed - Partridge, L., Fuentealba, M. & Kennedy, B.K. The quest to slow ageing through drug discovery. Nat Rev Drug Discov 19, 513–532 (2020). doi.org/10.1038/s41573-020-0067-7
eLife rapamycin - doi.org/10.7554/eLife.16351.001
Suggested Brian Kennedy interview (rapamycin)- lifespan.io/news/brian-kennedy-on-rapamycin-mtor-and-interventions
Rapamycin Opinion article - Aging (Albany NY). 2019 Oct 15; 11(19): 8048–8067.
Published online 2019 Oct 4. doi: 10.18632/aging.102355
Previous videos of use;
NAD - youtube.com/playlist?list=PLnLFbRYd2NGE83BwpXiWbhs2qokuP2TJ5
Icons in intro; "freepik.com/free-photos-vectors/background"Background vector created by freepik - freepik.com
There are more than 200 different geroprotective compounds. Some of these are already available as supplements, some are in clinical trials and some have FDA approval. Which are my top 5 that I think i most promising in terms of their anti-aging effects (so focusing more on healthspan than lifespan). And note the use of "promising" - there is still much work to be done to better investigate the long-term safety, dose and timings of different supplements which you should always bear in mind.
Anyway, I made this video more for a bit of fun and to make a longer summary video to pull ideas together from multiple previous videos with some new info too! So hope you like it!
Do my top 5 match yours?
#aging #anti-aging #supplements #nmn #akg
TIMESTAMPS:
Intro & useful resources - 00:00
Pick #1 - 03:10
Pick #2 - 06:14
Pick #3 - 08:52
Pick #4 - 11:24
Pick #5 - 12:54
Round-up - 15:28
Bonus #1 - 16:10
Bonus #2 - 16:25
References;
Check out @LifespanIO rejuvenation road map;
lifespan.io/road-maps/the-rejuvenation-roadmap
Nature comment - nature.com/articles/d41586-018-01668-0#:~:text=A%20class%20of%20drugs%20called,muscles%2C%20immune%20system%20and%20more.
AKG news - buckinstitute.org/news/a-metabolite-produced-by-the-body-increases-lifespan-and-dramatically-compresses-late-life-morbidity-in-mice
TAME trial - afar.org/tame-trial
Table I showed - Partridge, L., Fuentealba, M. & Kennedy, B.K. The quest to slow ageing through drug discovery. Nat Rev Drug Discov 19, 513–532 (2020). doi.org/10.1038/s41573-020-0067-7
eLife rapamycin - doi.org/10.7554/eLife.16351.001
Suggested Brian Kennedy interview (rapamycin)- lifespan.io/news/brian-kennedy-on-rapamycin-mtor-and-interventions
Rapamycin Opinion article - Aging (Albany NY). 2019 Oct 15; 11(19): 8048–8067.
Published online 2019 Oct 4. doi: 10.18632/aging.102355
Previous videos of use;
NAD - youtube.com/playlist?list=PLnLFbRYd2NGE83BwpXiWbhs2qokuP2TJ5
Icons in intro; "freepik.com/free-photos-vectors/background"Background vector created by freepik - freepik.com
