Uploaded January 2021 | Updated September 2026, 1 week ago
There is a wealth of evidence supporting the association between regular exercise and decreased cancer risk, but how and why? And can exercise really prevent tumour growth? Well, in this video I take a look at a recent publication showing cytotoxic t cells (CD8+ T-cells) may be mediating the observed exercise-induced tumour reduction. This can be understood by appreciating the hallmarks of cancer that includes evasion of immune destruction.
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DoNotAge are supporting my channel in the education of longevity and aging research. They also sell a variety of supplements including NMN, resveratrol, fisetin and more! :)
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TIMESTAMPS
Intro - 00:00
Exercise & Cancer - 00:39
Evading immune destruction - 02:00
How exercise reduces tumour growth? - 03:57
Lactate alone? - 07:00
Unanswered questions - 07:50
My thoughts & a question - 08:30
References;
Cytotoxic t-cells - Cite as: eLife 2020;9:e59996 DOI: 10.7554/eLife.59996
Review article - doi.org/10.1016/j.trecan.2017.04.007
Hallmarks of cancer doi.org/10.1016/j.cell.2011.02.013
Zhang, D., Tang, Z., Huang, H. et al. Metabolic regulation of gene expression by histone lactylation. Nature 574, 575–580 (2019). doi.org/10.1038/s41586-019-1678-1
Icons in intro; "freepik.com/free-photos-vectors/background"Background vector created by freepik - freepik.com
There is a wealth of evidence supporting the association between regular exercise and decreased cancer risk, but how and why? And can exercise really prevent tumour growth? Well, in this video I take a look at a recent publication showing cytotoxic t cells (CD8+ T-cells) may be mediating the observed exercise-induced tumour reduction. This can be understood by appreciating the hallmarks of cancer that includes evasion of immune destruction.
*Get 10% off at DoNotAge using my discount code "SHEEKEY"*
bit.ly/DoNotAgeProducts
DoNotAge are supporting my channel in the education of longevity and aging research. They also sell a variety of supplements including NMN, resveratrol, fisetin and more! :)
Disclaimer - using this discount will provide the channel with a small commission, so only use if you want to support the channel! :)
TIMESTAMPS
Intro - 00:00
Exercise & Cancer - 00:39
Evading immune destruction - 02:00
How exercise reduces tumour growth? - 03:57
Lactate alone? - 07:00
Unanswered questions - 07:50
My thoughts & a question - 08:30
References;
Cytotoxic t-cells - Cite as: eLife 2020;9:e59996 DOI: 10.7554/eLife.59996
Review article - doi.org/10.1016/j.trecan.2017.04.007
Hallmarks of cancer doi.org/10.1016/j.cell.2011.02.013
Zhang, D., Tang, Z., Huang, H. et al. Metabolic regulation of gene expression by histone lactylation. Nature 574, 575–580 (2019). doi.org/10.1038/s41586-019-1678-1
Icons in intro; "freepik.com/free-photos-vectors/background"Background vector created by freepik - freepik.com
