Why 20% of People Are Exercise Non-Responders @nicknorwitzMDPhD
Why 20% of People Are Exercise Non-Responders  @nicknorwitzMDPhD
Uploaded March 2026 | Updated September 2026, 1 week ago
Check out the muscle health archives here: staycuriousmetabolism.substack.com/p/musclehealth

Some people train consistently but see little progress—often labeled “exercise non-responders.” Emerging research suggests this may not be genetic, but linked to blood sugar. Elevated glucose can stiffen the muscle’s extracellular matrix, limiting the growth of new blood vessels needed for adaptation.

For more information, see the muscle health archives at staycuriousmetabolis.com, linked above

#ExerciseScience #BloodSugar #MetabolicHealth #MuscleGrowth #Angiogenesis #InsulinResistance #staycurious
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Nick Norwitz MD PhD |

Why 20% of People Are Exercise Non-Responders

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