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Levels | The Glycemic Index | Why Most People in the United States Don’t Feel Well | Dr. Casey Means @levels | Uploaded January 2024 | Updated October 2024, 10 hours ago.
Why diet is not one-size-fits-all and how you can find one that works for you.

Personalized Nutrition by Prediction of Glycemic Responses: levels.com/blog/why-are-glucose-responses-so-individual

Levels advisors Dr. Casey Means and Dr. Mark Hyman chat about bio-individuality, or how the same foods affect people differently.

🔬 Dr. Means shares info about a 2015 study published in the journal Cell (PMID: 26590418)

- Researchers used a continuous glucose monitor to track the glucose responses to nearly 50K meals in 800 adults who did not have type 2 diabetes.
- Each participant wore a CGM for 1 week and logged meals, physical activity, and sleep.
- They followed their normal routines and eating habits, except for their first meal of the day, which was 1 of 4 standard meal options.
- The scientists found a high interpersonal variability of glucose responses when different people ate the SAME meals.
- Some people’s glucose raised 10 mg/dL; others went up 100 mg/dL, again to the SAME foods.
- Researchers believe peoples’ microbiomes were a key factor in how they responded.
- They used machine learning to predict participants’ glucose responses.
- Factors included in the predicted response were a person’s blood parameters (e.g., blood pressure and cholesterol), gut microbiome, dietary habits, physical activity, and anthropometrics—body measurements.
- The researchers replicated their findings with a different group of 100 participants.
- They found that personalized dietary changes over just 1 week helped improve postprandial (after-meal) glucose responses and reduced glycemic variability.
- This is why we need ways of determining, in real time, how foods affect our individual health, rather than following one-size-fits-all dietary advice.

✅ Wearing a continuous glucose monitor can help you track your glucose responses. “It really comes down to choices,” Dr. Means says. “And right now we don’t have a lot of help to understand what choices to make for our own body. And that’s where wearables—especially bio wearables—can be very helpful.”

#metabolichealth #metabolism #CGM #levelshealth #healthtips #healthy #healthylife #bloodsugar

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Levels helps you see how food affects your health. With real-time, personalized data gathered through biosensors like continuous glucose monitors (CGM), you learn which diet and lifestyle choices improve your metabolic health so you can live a longer, fuller, healthier life.

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The Glycemic Index | Why Most People in the United States Don’t Feel Well | Dr. Casey Means @levels

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