Uploaded November 2021 | Updated September 2026, 1 week ago
The Mechanism for a pinacol–pinacolone rearrangement which is a method for converting a 1,2-diol to a carbonyl compound. The 1,2-rearrangement takes place under acidic conditions. The name of the rearrangement reaction comes from the rearrangement of pinacol to pinacolone. The driving force for this rearrangement step is believed to be the relative stability of the resultant oxonium ion. The migration of alkyl groups in this reaction occurs in accordance with their usual migratory aptitude, i.e. hydride, phenyl carbocation, tertiary carbocation (if formed by migration), secondary carbocation (if formed by migration), methyl carbocation
Music: It’s Not Your Toy – Mokka
The Mechanism for a pinacol–pinacolone rearrangement which is a method for converting a 1,2-diol to a carbonyl compound. The 1,2-rearrangement takes place under acidic conditions. The name of the rearrangement reaction comes from the rearrangement of pinacol to pinacolone. The driving force for this rearrangement step is believed to be the relative stability of the resultant oxonium ion. The migration of alkyl groups in this reaction occurs in accordance with their usual migratory aptitude, i.e. hydride, phenyl carbocation, tertiary carbocation (if formed by migration), secondary carbocation (if formed by migration), methyl carbocation
Music: It’s Not Your Toy – Mokka
