Uploaded May 2025 | Updated September 2026, 1 hour ago
Discover PacBio's accurate long-read HiFi sequencing for comprehensive cancer genomics, presented at AACR. This talk explores DNA, RNA, and epigenome insights.
Hear from PacBio's Alex Sockell on how HiFi reads (up to 25 kb, highly accurate) enable multi-omic views, crucial for characterizing structural variants, phasing mutations, identifying full-length RNA isoforms, and detecting methylation (5mC, 5hmC, 6mA). Learn about SPRQ chemistry and the Ampli-Fi protocol, allowing HiFi sequencing from low-input DNA (as little as 1 ng) and challenging samples like FFPE and cell-free DNA.
Guest speakers Bingqing Zhao (Stanford University) discusses a single-cell atlas for colorectal cancer progression, and Arthur Dondi (ETH Zurich) presents on genomic and transcriptomic variant detection in ovarian cancer using long-read single-cell RNA sequencing.
Subscribe to PacBio for more updates and share your thoughts in the comments.
youtube.com/channel/UC2y78sjVOumGc2da1tN629g
Learn more about PacBio at pacb.com
Legal & Trademarks: Visit pacb.com/legal-and-trademarks
Discover PacBio's accurate long-read HiFi sequencing for comprehensive cancer genomics, presented at AACR. This talk explores DNA, RNA, and epigenome insights.
Hear from PacBio's Alex Sockell on how HiFi reads (up to 25 kb, highly accurate) enable multi-omic views, crucial for characterizing structural variants, phasing mutations, identifying full-length RNA isoforms, and detecting methylation (5mC, 5hmC, 6mA). Learn about SPRQ chemistry and the Ampli-Fi protocol, allowing HiFi sequencing from low-input DNA (as little as 1 ng) and challenging samples like FFPE and cell-free DNA.
Guest speakers Bingqing Zhao (Stanford University) discusses a single-cell atlas for colorectal cancer progression, and Arthur Dondi (ETH Zurich) presents on genomic and transcriptomic variant detection in ovarian cancer using long-read single-cell RNA sequencing.
Subscribe to PacBio for more updates and share your thoughts in the comments.
youtube.com/channel/UC2y78sjVOumGc2da1tN629g
Learn more about PacBio at pacb.com
Legal & Trademarks: Visit pacb.com/legal-and-trademarks










