Uploaded May 2025 | Updated September 2026, 22 minutes ago
This tutorial guides users through installing SMRT Link, PacBio's software for instrument management, run setup, monitoring, and performance metric viewing. Rhett Rautsaw, Senior Field Applications Bioinformatic Support Scientist at PacBio, details the full on-premises SMRT Link installation process.
The video covers the different SMRT Link versions (Cloud, Lite, and Full), focusing on the full installation requirements, including supported operating systems (Ubuntu, Rocky) and recommended job management systems like SLURM. It outlines hardware specifications for head nodes and HPC clusters, directory setup, and the interactive installation steps. Learn how to configure SMRT Link for push-button secondary analysis and access its modules for instruments, sample setup, runs, data management, and SMRT Analysis.
00:00 Introduction to SMRT Link
00:34 SMRT Link Versions Explained
01:20 Full On-Premises Installation Focus
01:29 System Requirements & Recommendations
02:35 Storage Considerations
02:55 SMRT Link Modules Overview
03:14 Pre-Installation: User & Directory Setup
04:35 Downloading SMRT Link
05:08 Running the Interactive Installer
05:41 Installer Step 0: Prerequisite Check
06:14 Installer Step 1-2: User & Server Name
06:34 Installer Step 3: UI & Services Ports
06:52 Installer Step 4: SQL Database Setup
07:06 Installer Step 5: Cromwell Server Setup
07:16 Installer Step 6: Jobs & Temp Directories
07:50 Installer Step 7: PacBio Remote Services
08:01 Installer Step 8: Email Notifications (Optional)
08:08 Installer Step 9: Compute Configurations
09:56 Installer Step 10: Max Concurrent Workflows
10:13 Post-Installation Directory Structure
10:49 Starting SMRT Link Services
11:02 Accessing the SMRT Link UI
11:28 Initial Login & Key Settings
11:53 Running a Site Acceptance Test
12:08 Exploring SMRT Analysis Module
12:23 Conclusion & Further Resources
Subscribe for more insights from PacBio: youtube.com/@PacificBiosciences?sub_confirmation=1
Learn more about PacBio at pacb.com
Legal & Trademarks: Visit pacb.com/legal-and-trademarks
This tutorial guides users through installing SMRT Link, PacBio's software for instrument management, run setup, monitoring, and performance metric viewing. Rhett Rautsaw, Senior Field Applications Bioinformatic Support Scientist at PacBio, details the full on-premises SMRT Link installation process.
The video covers the different SMRT Link versions (Cloud, Lite, and Full), focusing on the full installation requirements, including supported operating systems (Ubuntu, Rocky) and recommended job management systems like SLURM. It outlines hardware specifications for head nodes and HPC clusters, directory setup, and the interactive installation steps. Learn how to configure SMRT Link for push-button secondary analysis and access its modules for instruments, sample setup, runs, data management, and SMRT Analysis.
00:00 Introduction to SMRT Link
00:34 SMRT Link Versions Explained
01:20 Full On-Premises Installation Focus
01:29 System Requirements & Recommendations
02:35 Storage Considerations
02:55 SMRT Link Modules Overview
03:14 Pre-Installation: User & Directory Setup
04:35 Downloading SMRT Link
05:08 Running the Interactive Installer
05:41 Installer Step 0: Prerequisite Check
06:14 Installer Step 1-2: User & Server Name
06:34 Installer Step 3: UI & Services Ports
06:52 Installer Step 4: SQL Database Setup
07:06 Installer Step 5: Cromwell Server Setup
07:16 Installer Step 6: Jobs & Temp Directories
07:50 Installer Step 7: PacBio Remote Services
08:01 Installer Step 8: Email Notifications (Optional)
08:08 Installer Step 9: Compute Configurations
09:56 Installer Step 10: Max Concurrent Workflows
10:13 Post-Installation Directory Structure
10:49 Starting SMRT Link Services
11:02 Accessing the SMRT Link UI
11:28 Initial Login & Key Settings
11:53 Running a Site Acceptance Test
12:08 Exploring SMRT Analysis Module
12:23 Conclusion & Further Resources
Subscribe for more insights from PacBio: youtube.com/@PacificBiosciences?sub_confirmation=1
Learn more about PacBio at pacb.com
Legal & Trademarks: Visit pacb.com/legal-and-trademarks
