Uploaded January 2025 | Updated September 2026, 1 day ago
Dr Lustig will discuss the best way to fix insulin resistance and the 5 types of fat you need to eat. Head to DrinkLMNT.com/theprimalpodcast to get your free sample pack with any purchase.
Fix Insulin Resistance (Free Guide): theprimal.com/lab/get-rid-of-insulin-resistance-once-for-all
In this episode, my guest is Dr. Robert Lustig, M.D., neuroendocrinologist, professor of pediatrics at the University of California, San Francisco (UCSF), and a bestselling author on nutrition and metabolic health. We discuss how to fix insulin resistance, the 3 ways you can become insulin resistant, and nutritional protocols to fix insulin resistance without medications.
Primal Resources
GoCarnivore App: gocarnivore.com
4-Week Fat Loss Course: academy.theprimal.com/carnivore-fat-loss-masterclass-4-week-kick-starter
7-Day Fasting Course For Fat Loss: academy.theprimal.com/fasting-101-for-fat-loss
The Primal Podcast
Website: theprimal.com
Instagram: instagram.com/theprimal.podcast
Twitter: https://x.com/ThePrimal_Pod
Timestamps
0:00 Intro
02:45 Insulin resistance prevalence
08:45 How insulin gets elevated in the body
21:40 Dr Robert Lustig's interest in metabolic health
35:33 Sugar + fructose causes insulin resistance
36:57 Fruit juice & fruit with insulin resistance
39:48 Diet sodas
42:16 The calories debate on metabolic health
45:30 Tool: What to eat to fix insulin resistance
49:31 Tool: High-fat diet to fix insulin resistance
53:50 Tool: Eat these fats to fix insulin resistance
01:00:24 Seeds oils & insulin resistance
01:06:02 Tool: Carbohydrates & insulin resistance
01:08:54 Fibre
01:16:25 Tool: Common signs of insulin resistance
01:17:51 Tool: Fasting insulin levels
01:18:43 Find Dr Robert Lustig
01:19:13 Free guide to fix insulin resistance with link
About Rina - The Primal Podcast
The Primal Podcast (previously known as 5 Minute Body) is hosted by Rina. For the past 3 years, Rina has been committed to improving people's health with nutrition by working with the best doctors and experts in health.
Her mission is to empower you with the knowledge, inspiration, and science-based tools to improve your health. We provide more health information and Carnivore challenges at theprimal.com
#insulinresistance
Dr Lustig will discuss the best way to fix insulin resistance and the 5 types of fat you need to eat. Head to DrinkLMNT.com/theprimalpodcast to get your free sample pack with any purchase.
Fix Insulin Resistance (Free Guide): theprimal.com/lab/get-rid-of-insulin-resistance-once-for-all
In this episode, my guest is Dr. Robert Lustig, M.D., neuroendocrinologist, professor of pediatrics at the University of California, San Francisco (UCSF), and a bestselling author on nutrition and metabolic health. We discuss how to fix insulin resistance, the 3 ways you can become insulin resistant, and nutritional protocols to fix insulin resistance without medications.
Primal Resources
GoCarnivore App: gocarnivore.com
4-Week Fat Loss Course: academy.theprimal.com/carnivore-fat-loss-masterclass-4-week-kick-starter
7-Day Fasting Course For Fat Loss: academy.theprimal.com/fasting-101-for-fat-loss
The Primal Podcast
Website: theprimal.com
Instagram: instagram.com/theprimal.podcast
Twitter: https://x.com/ThePrimal_Pod
Timestamps
0:00 Intro
02:45 Insulin resistance prevalence
08:45 How insulin gets elevated in the body
21:40 Dr Robert Lustig's interest in metabolic health
35:33 Sugar + fructose causes insulin resistance
36:57 Fruit juice & fruit with insulin resistance
39:48 Diet sodas
42:16 The calories debate on metabolic health
45:30 Tool: What to eat to fix insulin resistance
49:31 Tool: High-fat diet to fix insulin resistance
53:50 Tool: Eat these fats to fix insulin resistance
01:00:24 Seeds oils & insulin resistance
01:06:02 Tool: Carbohydrates & insulin resistance
01:08:54 Fibre
01:16:25 Tool: Common signs of insulin resistance
01:17:51 Tool: Fasting insulin levels
01:18:43 Find Dr Robert Lustig
01:19:13 Free guide to fix insulin resistance with link
About Rina - The Primal Podcast
The Primal Podcast (previously known as 5 Minute Body) is hosted by Rina. For the past 3 years, Rina has been committed to improving people's health with nutrition by working with the best doctors and experts in health.
Her mission is to empower you with the knowledge, inspiration, and science-based tools to improve your health. We provide more health information and Carnivore challenges at theprimal.com
#insulinresistance
![Neuroscientist: #1 Way To Lose Weight & Double Autophagy [EAT THIS]](https://i.ytimg.com/vi/hzU7mLn6A1A/mqdefault.jpg "Neuroscientist: #1 Way To Lose Weight & Double Autophagy [EAT THIS]
The science-backed protocol to double autophagy and lose weight using sardine fasting, with Dr. Dom D’Agostino. Try ARMRA Colostrum for yourself, go to https://armra.com/theprimalpodcast or enter code THEPRIMALPODCAST to get 15% off your first order.
Is there a single metabolic switch that can accelerate weight loss while repairing your cells? In this episode, world-renowned metabolic researcher Dr. Dom D’Agostino (PhD) joins us to explain the science of autophagy, ketosis, and the gut microbiome. Referencing decades of laboratory research and clinical observation, Dr. D’Agostino explains why the traditional calories in, calories out model fails to account for cellular signaling and nutrient density. From the specific biochemical benefits of sardine fasting to the role of ketones in preserving gut barrier integrity, this conversation provides the medical clarity needed to optimize your biology. Whether you are looking to reverse metabolic dysfunction or seeking the latest data on nutritional ketosis, this episode bridges the gap between science and practical human experience.
In This Episode, We Reveal:
* The Autophagy Switch: A scientific breakdown of how to double cellular cleanup and the specific dietary triggers that initiate protein recycling.
* The Sardine Fasting Protocol: Why this specific high-protein, high-omega-3 approach is a clinical powerhouse for metabolic health and rapid ketosis.
* Ketosis & Disease Prevention: Moving beyond the scale to understand how ketones function as signaling molecules for longevity and neuroprotection.
* Gut Barrier Integrity: The relationship between the microbiome and metabolic health, and why maintaining the gut lining is the first line of defense against systemic inflammation.
* Translating Research to Reality: How to apply cutting-edge metabolic data to daily life for sustainable weight loss and disease prevention.
Our Sponsor:
ARMRA: Try ARMRA Colostrum for yourself, go to armra.com/theprimalpodcast or enter code THEPRIMALPODCAST to get 15% off your first order. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
MeatStock: Get $100 off every ticket, that’s a 25% discount, exclusively at https://www.theprimal.com/meatstock-2026-tickets
Scientific Resources & Dr. D’Agostino’s Work:
* Journal Article: Ketogenic Diet and Metabolic Health (Springer): https://link.springer.com/article/10.1186/s12916-024-03775-4
* Clinical Research: Metabolic Switching and Health (PubMed): https://pubmed.ncbi.nlm.nih.gov/37057184/
* Historical Context: Nutritional Ketosis in Medicine (PubMed): https://pubmed.ncbi.nlm.nih.gov/41562187/
* Dr. DAgostino’s Website & Research: https://ketonutrition.org/
Timestamps:
00:00 – Intro
02:11 – The One Biomarker That Rules Them All
04:27 – What Is Sardine Fasting?
12:05 – His Body Changed In 3 Days
15:39 – Does Sardine Fasting Target Visceral Fat?
16:33 – His Insulin Was Flagged As Too Low
18:25 – The Cholesterol Debate On Keto
21:42 – Bone Health On A Ketogenic Diet
25:13 – Which Sardines To Buy And How Often
28:14 – The 3-Day Monthly Reset
31:45 – What Ketosis Does To Your Gut
34:34 – Can Ketones Protect Your Brain?
37:46 – The Powerlifter Who Was Told Hed Die
44:44 – Ketones And The Longevity Pathways
50:10 – The Blood Marker More Important Than LDL
55:36 – Does MCT Oil Actually Boost Ketones?
59:37 – Five Foods A Neuroscientist Eats Daily
01:09:43 – The One Keto Food Quietly Killing Your Results
Primal Resources:
* Primal Tallow Balms & Soaps: https://shop.theprimal.com/
* GoCarnivore App: https://www.gocarnivore.com/
Connect With Us:
* Website: https://www.theprimal.com/
* Instagram: @theprimal.podcast
* Twitter/X: @ThePrimal_Pod
About Rina Ahluwalia & The Primal Podcast: Rina Ahluwalia is a leading researcher in root-cause healing and the founder of GoCarnivore.com. She facilitates high-level clinical discussions with world-renowned MDs and researchers to deconstruct the pathophysiology of modern disease and promote the science of the Proper Human Diet.
Medical Disclaimer Note: The content provided in this video and description is for educational and informational purposes only. It is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have heard on this channel.")
