Uploaded March 2026 | Updated September 2026, 1 week ago
LINK: open.substack.com/pub/staycuriousmetabolism/p/retas-big-promise-lose-one-third?r=40ekz2&utm_campaign=post&utm_medium=web&showWelcomeOnShare=true
Retatrutide is a new weight-loss drug that activates three hormone pathways (GLP-1, GIP, and glucagon) and has been getting a lot of attention. Some people claim it helps protect muscle during weight loss. But the data say otherwise. In the primary study with DXA scan, data participants lost about 6.5 kg (≈14 lb) of lean mass, which was roughly 38% of the total weight lost.
For the full mechanisms, limitations, and nuance, watch the long-form breakdown linked above.
#Retatrutide #GLP1 #WeightLossScience #MetabolicHealth #LeanMass #HealthResearch #StayCurious
LINK: open.substack.com/pub/staycuriousmetabolism/p/retas-big-promise-lose-one-third?r=40ekz2&utm_campaign=post&utm_medium=web&showWelcomeOnShare=true
Retatrutide is a new weight-loss drug that activates three hormone pathways (GLP-1, GIP, and glucagon) and has been getting a lot of attention. Some people claim it helps protect muscle during weight loss. But the data say otherwise. In the primary study with DXA scan, data participants lost about 6.5 kg (≈14 lb) of lean mass, which was roughly 38% of the total weight lost.
For the full mechanisms, limitations, and nuance, watch the long-form breakdown linked above.
#Retatrutide #GLP1 #WeightLossScience #MetabolicHealth #LeanMass #HealthResearch #StayCurious
