Uploaded April 2026 | Updated September 2026, 1 week ago
Deep dive here:
staycuriousmetabolism.substack.com/p/the-hidden-way-sleep-loss-drives?r=40ekz2&utm_campaign=post&utm_medium=web&triedRedirect=true
In a study published in Nature, sleep deprivation was shown to directly accelerate atherosclerosis. Sleep loss suppresses the arousal hormone hypocretin (orexin), which signals the bone marrow to overproduce inflammatory immune cells that migrate to arteries and drive plaque growth. For the full mechanism, human relevance, and actioable insights, see the deep dive linked above.
#SleepScience #HeartHealth #Atherosclerosis #Neuroscience #Immunology #PreventiveHealth
Deep dive here:
staycuriousmetabolism.substack.com/p/the-hidden-way-sleep-loss-drives?r=40ekz2&utm_campaign=post&utm_medium=web&triedRedirect=true
In a study published in Nature, sleep deprivation was shown to directly accelerate atherosclerosis. Sleep loss suppresses the arousal hormone hypocretin (orexin), which signals the bone marrow to overproduce inflammatory immune cells that migrate to arteries and drive plaque growth. For the full mechanism, human relevance, and actioable insights, see the deep dive linked above.
#SleepScience #HeartHealth #Atherosclerosis #Neuroscience #Immunology #PreventiveHealth
