The Sheekey Science Show | AKG prevents age-related bone loss? (& free giveaway) @TheSheekeyScienceShow | Uploaded November 2020 | Updated October 2024, 4 days ago.
More good news for potential osteoporosis treatments this year. Following on from my previous video looking at how warmth-induced changes within the microbiome prevented decline in bone mass seen in osteoporosis, this new study shows how alpha-ketoglutarate (AKG) may have a similar effect. The study shows in mice that AKG increases bone mass in aged mice suggesting that AKG could be used to prevent age-related bone loss.
Also at the end I will be revealing a free supplement giveaway!
*Get 10% off at DoNotAge using my discount code "SHEEKEY"*
bit.ly/Sheekey_DoNotAgeShop
DoNotAge are supporting my channel in the education of longevity and aging research. They also sell a variety of supplements including NMN, resveratrol, fisetin and more! :)
Disclaimer - using this discount will provide the channel with a small commission, so only use if you want to support the channel! :)
Also, I am not a medical doctor and check with your doctor/do your own research before taking any supplements.
TIMESTAMPS;
Intro - 00:00
What is AKG? 01:20
New study results - 02:30
Relating to other AKG data & thoughts - 09:20
Free giveaway & how to enter - 11:00
References;
Wang, Y., Deng, P., Liu, Y. et al. Alpha-ketoglutarate ameliorates age-related osteoporosis via regulating histone methylations. Nat Commun 11, 5596 (2020). [doi.org/10.1038/s41467-020-19360-1](doi.org/10.1038/s41467-020-19360-1)
Tocaj A, Filip R, Lindergard B, Wernerman J, Studzinski T, Ohman K, Pierzynowski S. Alpha-ketoglutarate (AKG) inhibit osteoporosis development in postmenopausal women; Journal of Bone and Mineral Research; 2003. pp. S267–S267. Amer Soc Bone & Mineral Res 2025 M St, Nw, Ste 800, Washington Dc 20036-3309 USA. [Google Scholar]
Icons in intro; "freepik.com/free-photos-vectors/background"Background vector created by freepik - freepik.com
More good news for potential osteoporosis treatments this year. Following on from my previous video looking at how warmth-induced changes within the microbiome prevented decline in bone mass seen in osteoporosis, this new study shows how alpha-ketoglutarate (AKG) may have a similar effect. The study shows in mice that AKG increases bone mass in aged mice suggesting that AKG could be used to prevent age-related bone loss.
Also at the end I will be revealing a free supplement giveaway!
*Get 10% off at DoNotAge using my discount code "SHEEKEY"*
bit.ly/Sheekey_DoNotAgeShop
DoNotAge are supporting my channel in the education of longevity and aging research. They also sell a variety of supplements including NMN, resveratrol, fisetin and more! :)
Disclaimer - using this discount will provide the channel with a small commission, so only use if you want to support the channel! :)
Also, I am not a medical doctor and check with your doctor/do your own research before taking any supplements.
TIMESTAMPS;
Intro - 00:00
What is AKG? 01:20
New study results - 02:30
Relating to other AKG data & thoughts - 09:20
Free giveaway & how to enter - 11:00
References;
Wang, Y., Deng, P., Liu, Y. et al. Alpha-ketoglutarate ameliorates age-related osteoporosis via regulating histone methylations. Nat Commun 11, 5596 (2020). [doi.org/10.1038/s41467-020-19360-1](doi.org/10.1038/s41467-020-19360-1)
Tocaj A, Filip R, Lindergard B, Wernerman J, Studzinski T, Ohman K, Pierzynowski S. Alpha-ketoglutarate (AKG) inhibit osteoporosis development in postmenopausal women; Journal of Bone and Mineral Research; 2003. pp. S267–S267. Amer Soc Bone & Mineral Res 2025 M St, Nw, Ste 800, Washington Dc 20036-3309 USA. [Google Scholar]
Icons in intro; "freepik.com/free-photos-vectors/background"Background vector created by freepik - freepik.com
