Uploaded November 2025 | Updated September 2026, 1 week ago
You can view Dr. Gombolay's presentation slides here:
files.wearesrna.org/symposia/2025_rnds/slides/2025RNDS-Research_Emory_Atlanta-Grace_Gombolay.pdf
In this session of the 2025 RNDS, Drs. Grace Gombolay, Varun Kannan, and Spencer Hutto of Emory University discussed current and prospective research at their facility. Some of the research topics include the efficacy of IVIG as a long-term treatment for MOGAD and PLEX as a short-term treatment, which diets are best for people with rare neuroimmune disorders, the capacity for early differentiation in disorders through MRI imaging, MRI techniques to examine blood-brain barrier injury, and leptomeningeal enhancement in MOGAD.
Future work includes utilizing AI to help with earlier diagnosis, creating an international treatment consensus for MOGAD, and understanding predictive markers. They are currently seeking to create a patient registry, collecting blood and cerebro-spinal fluid to look for biomarkers for relapse. Audience members asked questions about the glymphatic system, funding clinical research, and how patients and advocacy organizations can get involved.
You can view Dr. Gombolay's presentation slides here:
files.wearesrna.org/symposia/2025_rnds/slides/2025RNDS-Research_Emory_Atlanta-Grace_Gombolay.pdf
In this session of the 2025 RNDS, Drs. Grace Gombolay, Varun Kannan, and Spencer Hutto of Emory University discussed current and prospective research at their facility. Some of the research topics include the efficacy of IVIG as a long-term treatment for MOGAD and PLEX as a short-term treatment, which diets are best for people with rare neuroimmune disorders, the capacity for early differentiation in disorders through MRI imaging, MRI techniques to examine blood-brain barrier injury, and leptomeningeal enhancement in MOGAD.
Future work includes utilizing AI to help with earlier diagnosis, creating an international treatment consensus for MOGAD, and understanding predictive markers. They are currently seeking to create a patient registry, collecting blood and cerebro-spinal fluid to look for biomarkers for relapse. Audience members asked questions about the glymphatic system, funding clinical research, and how patients and advocacy organizations can get involved.


![Community Meets Clinic 302. Drs. Grace Gombolay and Varun Kannan
The Community Meets Clinic podcast series introduces clinicians and healthcare personnel specializing in rare neuroimmune disorders. In this episode hosted by Krissy Dilger of SRNA, we met Dr. Grace Gombolay and Dr. Varun Kannan, both from Emory University and Childrens Healthcare of Atlanta, designated Centers of Excellence in Rare Neuroimmune Disorders. Dr. Kannan discussed learning alongside families as conditions like MOG antibody disease emerged clinically and his focus on tailoring treatment and supporting clinical trials in a field with few approved therapies [03:37]. Dr. Gombolay outlined her research on biomarker development, a Children’s biobank, advanced MRI collaborations, and participation in the Network of Pediatric MS Centers covering disorders such as MOGAD, NMOSD, optic neuritis, ADEM, and TM [06:36]. They described their multidisciplinary clinic team, highlighted home infusions and telemedicine to reduce burden, and shared personal self-care strategies [10:22]. Dr. Gombolay and Dr. Kannan expressed hope for more trials, remyelination, prevention, and earlier diagnosis aided by AI prompts [20:43].
You can view Dr. Grace Gombolays medical profile here:
https://www.choa.org/doctors/grace-gombolay
You can view Dr. Varun Kannans medical profile here:
https://www.choa.org/doctors/varun-kannan
Grace Gombolay, MD, MSc, FAAN is an Associate Professor at Emory University and Director of the Pediatric Neuroimmunology and Multiple Sclerosis Clinic at Childrens Healthcare of Atlanta. Her research interest involves biomarker development in pediatric neuroinflammatory diseases including autoimmune encephalitis, multiple sclerosis, MOGAD, and NMOSD.
Varun Kannan, MD graduated from Emory University School of Medicine in 2017. He then completed child neurology residency in 2022, followed by pediatric neuroimmunology and multiple sclerosis fellowship at Baylor College of Medicine and Texas Childrens Hospital in 2023. He returned to Emory and Childrens Healthcare of Atlanta in 2023, where he has worked closely with Dr. Grace Gombolay in the neuroimmunology program. He is interested in clinical research regarding severe/relapsing forms of rare neuroimmune disorders including autoimmune encephalitis and MOGAD. He is currently involved in multiple upcoming phase 3 clinical trials exploring new disease modifying treatments for pediatric rare neuroimmune disorders. He is also passionate about medical education and is currently one of the Associate Program Directors for the Emory child neurology residency.
00:00 Welcome
01:56 Dr. Grace Gombolays Journey
03:37 Dr. Varun Kannans Path
05:06 Kannans Research Focus
06:36 Biomarkers and Biobank
10:22 Clinic Team and Care
13:44 Self Care and Balance
16:15 Childrens Healthcare of Atlanta
20:43 Hopeful Future Ahead
24:49 Closing Community Meets Clinic 302. Drs. Grace Gombolay and Varun Kannan](https://i.ytimg.com/vi/hUrRjRHM69s/mqdefault.jpg)
![201. Steroid Dependence
In this ABCs of MOGAD episode, Steroid Dependence, Krissy Dilger of SRNA was joined by Dr. Eoin Flanagan from the Mayo Clinic in Rochester, MN. They began with a summary of how steroids are used to manage MOG antibody disease, particularly during acute attacks [00:01:25]. Dr. Flanagan described the mechanics of steroids in reducing brain inflammation and the importance of early treatment [00:04:14]. They discussed the concept of steroid dependence and the complications that arise when tapering down the steroid dose [00:05:46]. Dr. Flanagan highlighted alternative treatments to manage steroid dependence and emphasized the importance of working closely with healthcare providers to safely reduce steroid use over time [00:09:42].
Eoin Flanagan, MB, BCh is a Professor of Neurology and Consultant in the departments of Neurology and Laboratory Medicine and Pathology at the Mayo Clinic (Rochester, MN). He completed his medical school training at University College Dublin in Ireland in 2005. He did a medical residency in Ireland and then completed neurology residency, fellowships in neuroimmunology and a masters in clinical and translational science at Mayo Clinic (Rochester, MN). He works in the Autoimmune Neurology and Multiple Sclerosis Clinics and the Neuroimmunology Laboratory at the Mayo Clinic.
His clinical expertise and research are focused on inflammatory myelopathies and their imaging patterns, myelin oligodendrocyte glycoprotein (MOG) antibody associated disorder, neuromyelitis optica spectrum disorders, autoimmune encephalitis, paraneoplastic neurologic disorders, and multiple sclerosis. He is principal investigator on an NIH RO1 grant studying MOG antibody associated disorder.
00:00 Introduction
01:25 Understanding Steroids in MOG Antibody Disease
04:14 Steroid Dosage and Administration
05:46 Steroid Dependence in MOGAD Patients
09:42 Managing Steroid Dependence
14:02 Balancing Inflammation Control and Steroid Risks
17:31 Conclusion 201. Steroid Dependence](https://i.ytimg.com/vi/hkXutCNesok/mqdefault.jpg)
![2024 RNDS | What’s my Diagnosis? Physician Panel Discussion Based on Community Panel Presentations
At the 2024 RNDS, a panel of physicians discussed the community panel presentations on their diagnostic journey. The panel collectively discussed the importance of integrating patient stories with clinical perspectives to improve diagnosis and treatment of rare neurologic disorders [00:03:15]. Dr. Carlos Pardo shared historical insights and reviewed the evolution and challenges in understanding and diagnosing transverse myelitis over the past 20 years [00:06:23]. Dr. Dean Wingerchuk highlighted the journey and breakthroughs regarding neuromyelitis optica, emphasizing the significance of biomarkers and new diagnostic criteria [00:18:47]. Dr. Leslie Benson and others delved into acute flaccid myelitis, discussing how it overlaps and differentiates from other conditions, underscoring the importance of precise diagnostic methods and long-term management [00:35:12]. Please note that the information shared during this session is for informational purposes only and is not medical advice.
00:00 Welcome and Introduction
01:13 Historical Perspective on Neurological Disorders
10:52 The Evolution of Neuromyelitis Optica
19:03 The Role of Diagnostic Testing
26:07 Acute Flaccid Myelitis: A New Challenge
37:43 The Importance of Accurate Diagnosis and Long-term Management
42:33 Advice for Patients and Families
46:01 Closing Remarks and Acknowledgements 2024 RNDS | What’s my Diagnosis? Physician Panel Discussion Based on Community Panel Presentations](https://i.ytimg.com/vi/iGsNACIp5Ds/mqdefault.jpg)

![Ask the Expert 1409. Community Spotlight | Cindy Ranii
In this Community Spotlight Edition of Ask the Expert, Landy Thomas of SRNA spoke with Cindy Ranii about living with transverse myelitis (TM). Cindy described her diagnostic journey, rehabilitation, accessibility, and financial challenges [00:53]. She discussed returning to work briefly before retiring, emphasizing the importance of support, love, and community [08:51]. Cindy shared her path from wheelchair tennis to international wheelchair table tennis, and her pursuit of Paralympic qualification through point-based global competition [13:17]. She also discussed writing and self-publishing her book, Parakeet Races and Other Stories, inspired by family memories and her experience with TM [31:58].
Cindy Ranii is a 79-year-old retired educator who lives with her wife Shelly and service dog Hollis in Santa Cruz, California. In 2005, her life changed drastically when she was diagnosed with transverse myelitis (TM). Within four days, she went from golfing, playing tennis, and working vigorously as the Superintendent of a local high school district to being a paraplegic (T-3 complete).
Six months after her diagnosis she was back at work, using a wheelchair fulltime. Eighteen months later she decided to retire to have enough energy to enjoy her family (four children and 13 grandchildren) and to rebuild an active lifestyle. She competed in wheelchair tennis and then pursued table tennis with her eyes on the Paralympics. Currently she is training to compete in the 2028 LA Paralympics in wheelchair table tennis, saying, “My quest is to be the oldest Paralympian in history. It’s a long shot; but why not!”
Cindy has written numerous articles regarding living with a disability for New Mobility Magazine and authored a memoir, Parakeet Races and Other Stories, which is available through Amazon:
https://rebrand.ly/cindy-ranii
00:00 Welcome
00:53 Cindys Diagnosis Overview
01:37 Early Symptoms and ER Rush
06:07 Hospital Transfer and TM Diagnosis
08:51 Rehab Reality and New Life
11:27 Accessibility Costs and Support
13:17 Paralympic Table Tennis Quest
17:52 Disability Community and Pride
20:25 Finding Resilience Through Sport
22:34 Mentors and New Athletic Path
28:27 Work Return Then Retirement
31:58 Writing Her Memoir
37:09 Closing Reflections Ask the Expert 1409. Community Spotlight | Cindy Ranii](https://i.ytimg.com/vi/jGyRK8lTVGY/mqdefault.jpg)
![2024 RNDS | Adaptive Tools and Resources
At the 2024 RNDS, Sandy Hanebrink discussed various adaptive tools and resources available for individuals with disabilities, including driving aids, home modifications, and vision technology [00:01:52]. She highlighted innovative devices such as OrCam and Glidance to assist with vision and mobility, as well as affordable solutions for adaptive grips and accessible computer access [00:07:16]. Sandy also mentioned adaptive recreation tools, including wheelchairs and accessible gaming controllers, as well as funding sources for these technologies [00:13:48]. She concluded by informing the audience about the Abilities Expo and providing her contact information for further assistance [00:20:15]. Please note that the information shared during this session is for informational purposes only and is not medical advice.
You can view the presentation slides here:
https://files.wearesrna.org/symposia/2024_rnds/slides/2024RNDS_Hanebrink.pdf
00:00 Introduction and Background
00:32 Adaptive Driving Tools and Resources
01:42 Home Modifications for Accessibility
04:59 Vision Tools and Technologies
10:27 Adaptive Grips and Computer Access
16:22 Accessible Gaming and Mounts
18:04 Wheelchairs and Mobility Aids
20:24 Adaptive Recreation and Sports
23:00 NextGen TV and Accessible Media
25:27 Funding and Resources
27:31 Conclusion and Contact Information 2024 RNDS | Adaptive Tools and Resources](https://i.ytimg.com/vi/ji5uHddIJF8/mqdefault.jpg)


