Uploaded November 2025 | Updated September 2026, 1 week ago
During this panel at the 2025 RNDS, Drs. Spencer Hutto, Jacqueline Rosenthal, and Varun Kannan spoke about the diagnosis of rare diseases, including ADEM, AFM, MOGAD, NMOSD, ON, and TM. They answered audience questions about whether a viral component like Epstein-Barr can trigger rare neuroimmune disorders, whether transverse myelitis can affect the esophagus, how much spinal fluid is needed to run tests, and whether these disorders are hereditary.
During this panel at the 2025 RNDS, Drs. Spencer Hutto, Jacqueline Rosenthal, and Varun Kannan spoke about the diagnosis of rare diseases, including ADEM, AFM, MOGAD, NMOSD, ON, and TM. They answered audience questions about whether a viral component like Epstein-Barr can trigger rare neuroimmune disorders, whether transverse myelitis can affect the esophagus, how much spinal fluid is needed to run tests, and whether these disorders are hereditary.




![2024 RNDS | Fatigue and Rare Neuroimmune Disorders
At the 2024 RNDS, Dr. Bardia Nourbakhsh, an MS neurologist, discussed the complexities of fatigue in neuroimmune disorders and highlighted its subjective nature and overlapping symptoms with other conditions like depression and sleepiness [00:03:11]. He emphasized that defining and measuring fatigue is challenging, and current treatment approaches are often inadequate, especially in rare neuroimmune disorders [00:09:01]. Julia Lefelar shared her personal experience with MOG antibody disease (MOGAD) and highlighted the significant impact of fatigue on patients lives [00:20:48]. They answered questions from the audience and underscored the need for more research, patient-reported outcomes, and nonpharmacological treatments like cognitive behavioral therapy and exercise [00:27:08]. Please note that the information shared during this session is for informational purposes only and is not medical advice.
You can view the presentation slides here:
https://files.wearesrna.org/symposia/2024_rnds/slides/2024RNDS_Nourbakhsh.pdf
00:00 Introduction and Opening Remarks
00:31 Julia Lefelars Personal Experience with Fatigue
03:11 Understanding Fatigue in Medical Terms
09:01 Causes and Measurement of Fatigue
12:22 Treatment Approaches for Fatigue
20:48 Fatigue in Rare Neuroimmune Disorders
27:08 Audience Questions and Closing Remarks 2024 RNDS | Fatigue and Rare Neuroimmune Disorders](https://i.ytimg.com/vi/mCabRDJCReU/mqdefault.jpg)





