Uploaded January 2026 | Updated September 2026, 1 week ago
LINK: open.substack.com/pub/staycuriousmetabolism/p/this-drug-raises-ldl-cholesteroland?r=40ekz2&utm_campaign=post&utm_medium=web&showWelcomeOnShare=true
A class of medication’s known as SGLT2 inhibitors can improve cardiovascular outcomes while paradoxically raising LDL cholesterol and promoting hepatic ketogenesis. The increases in cholesterol are not large, but they’re instructive…
And certainly, they contradict the narrative that LDL cholesterol is the most important marker when it comes to heart health.
But for the nuances, you’ll need to read the letter or await the long-form video..
#cardiology #cholesterol #LDL #hearthealth #diabetes #medicalscience #staycurious
LINK: open.substack.com/pub/staycuriousmetabolism/p/this-drug-raises-ldl-cholesteroland?r=40ekz2&utm_campaign=post&utm_medium=web&showWelcomeOnShare=true
A class of medication’s known as SGLT2 inhibitors can improve cardiovascular outcomes while paradoxically raising LDL cholesterol and promoting hepatic ketogenesis. The increases in cholesterol are not large, but they’re instructive…
And certainly, they contradict the narrative that LDL cholesterol is the most important marker when it comes to heart health.
But for the nuances, you’ll need to read the letter or await the long-form video..
#cardiology #cholesterol #LDL #hearthealth #diabetes #medicalscience #staycurious
