Targeted capture for long transcripts using Samplix Xdrop @PacificBiosciences

Uploaded April 2025 | Updated September 2026, 2 hours ago

PacBio long-read sequencing can sequence full-length transcripts, but the capture of ultra-long transcripts (greater than 15kb) might be limited by typical cDNA synthesis methods. Nick Zomer at Radboud University Medical Center shows how using Samplix Xdrop technology to indirectly capture two genes associated with Usher syndrome type 2A, a genetic disease that results in hearing and vision loss.

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