Uploaded June 2023 | Updated September 2026, 1 hour ago
Reconstructing complete phased genomes is key to understanding the genetic basis of many complex traits. However, the bioinformatic complexity of long-range phasing creates a pressing need for streamlined, efficient computational approaches that can reconstruct high-quality, chromosome-scale phased sequences at scale.
Highly accurate long reads from PacBio (HiFi reads) are well suited for haplotype-resolved assemblies of human, non-human, and cancer genomes. With the right bioinformatics tools, HiFi data enables high-quality phased genome assembly to examine structural variant landscapes, characterize cancer-related mutations, and facilitate new, unbiased studies of haplotype variation.
In this webinar, Shilpa Garg, PhD, associate professor at DTU Biosustain, discusses:
• The need for chromosome-scale phasing in reference genomes
• Efficient and accurate haplotype-resolved human genome assembly
• Generalized graph-based methods for phased assembly of cancer genomes
Learn more about PacBio at pacb.com
Legal & Trademarks: Visit pacb.com/legal-and-trademarks
Reconstructing complete phased genomes is key to understanding the genetic basis of many complex traits. However, the bioinformatic complexity of long-range phasing creates a pressing need for streamlined, efficient computational approaches that can reconstruct high-quality, chromosome-scale phased sequences at scale.
Highly accurate long reads from PacBio (HiFi reads) are well suited for haplotype-resolved assemblies of human, non-human, and cancer genomes. With the right bioinformatics tools, HiFi data enables high-quality phased genome assembly to examine structural variant landscapes, characterize cancer-related mutations, and facilitate new, unbiased studies of haplotype variation.
In this webinar, Shilpa Garg, PhD, associate professor at DTU Biosustain, discusses:
• The need for chromosome-scale phasing in reference genomes
• Efficient and accurate haplotype-resolved human genome assembly
• Generalized graph-based methods for phased assembly of cancer genomes
Learn more about PacBio at pacb.com
Legal & Trademarks: Visit pacb.com/legal-and-trademarks
