Uploaded January 2026 | Updated September 2026, 1 day ago

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How can you be certain that your high-molecular-weight DNA is optimized for HiFi sequencing? In this PacBio Compatible Partner feature from our "SPRQ Your Research" series, Jonathan Hagopian, PhD, of Agilent Technologies introduces a critical quality control solution.

Discover the Agilent Femto Pulse system, an automated electrophoresis instrument recommended for crucial QC checkpoints in the HiFi whole genome sequencing workflow. Learn how its ability to accurately size large DNA fragments up to 165 kb and its high sensitivity can help you conserve precious sample material while ensuring optimal data quality and sequencer performance. This video details the three key stages where PacBio recommends a QC check—after extraction, after shearing, and before library creation—to help you achieve high-quality results for applications like scaling population genomics.

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