Q&A: Insulin resistance and hypertrophy, stimulant metabolism, and BMR variability (Ep 126) @strongerbyscience
Q&A: Insulin resistance and hypertrophy, stimulant metabolism, and BMR variability (Ep 126)  @strongerbyscience
Uploaded February 2024 | Updated September 2026, 3 days ago
In this Q&A episode of the podcast, Greg and Lyndsey answer questions about how to research a new subject, the effect of diabetes or insulin resistance on hypertrophy, how a pump might affect moment arms in movements, how much is too much isolation work, and more. They also give an update on the future of the podcast and announce that Dr Pak and Dr Milo Wolf are teaming up with Stronger By Science.

*TIME STAMPS*

00:00:00 – Podcast Updates
strongerbyscience.com/future

00:21:29 – Q&A Intro and "How do you go about researching a whole new subject?" (Q1 from Teo)

00:39:29 – "Does T2DM make hypertrophy impossible?" (Q2 from Jon)
strongerbyscience.com/p-ratios
strongerbyscience.com/p-ratios-rebuttal
strongerbyscience.com/p-ratios-rebuttal-2
pubmed.ncbi.nlm.nih.gov/32067343
ncbi.nlm.nih.gov/pmc/articles/PMC7068252
pubmed.ncbi.nlm.nih.gov/28441958
pubmed.ncbi.nlm.nih.gov/31557380

00:55:18 – "Does getting a pump increase strength?" (Q3 from Alexander)
strongerbyscience.com/size-vs-strength
peerj.com/articles/1462

01:05:20 – Stimulant metabolism (Q4 from Connor Smith)

01:17:40 – "How much can BMR vary between individuals?" (Q5 from Jon)
macrofactorapp.com/metabolism

01:29:35 – "Is it possible to taper down activity levels (steps) without reducing calories?" (Q6 from Angela)
ncbi.nlm.nih.gov/pmc/articles/PMC4803033

01:41:10 – "How do you incorporate plyometrics and explosive training for jump height" (Q8 from trugor)

01:54:29 – "Is there any research showing damage to the blood vessels or whatnot in the longer term due to the blood pressure increase, because of bracing/Valsalva maneuver?" (Q9 from No_Performer_8133)

pubmed.ncbi.nlm.nih.gov/23231790
pubmed.ncbi.nlm.nih.gov/33737330
pubmed.ncbi.nlm.nih.gov/38142405
02:00:51 – "How much isolation work is too much?" (Q10 from tompa01)

02:10:05 – "Favorite and least favorite things I’ve cooked" (Q11 from Ali Shah)

*RECOMMENDATIONS AND MORE FROM SBS*
Coaching: strongerbyscience.com/coaching
Bulksupplements.com: SBSPOD = 5% discount
MacroFactor nutrition app: macrofactorapp.com
MASS research review: massresearchreview.com
Stronger by Science Facebook group: facebook.com/groups/StrongerByScienceCommunity
Stronger by Science subreddit: reddit.com/r/StrongerByScience
Send your Q&A questions to podcast@strongerbyscience.com
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Q&A: Insulin resistance and hypertrophy, stimulant metabolism, and BMR variability (Ep 126)

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