Uploaded January 2026 | Updated September 2026, 1 week ago
LINK: open.substack.com/pub/staycuriousmetabolism/p/nattokinase-the-heart-health-supplement?r=40ekz2&utm_campaign=post&utm_medium=web&showWelcomeOnShare=true
Nattokinase is trending—but what is it, and can it actually impact atherosclerosis? In one study with over 1,000 participants taking 10,800 units daily for a year, researchers reported a 21.7% reduction in atherosclerosis measured by carotid intima-media thickness (CIMT), an ultrasound-based marker of arterial wall thickening. The results are interesting—and the mechanisms are too: nattokinase may support blood pressure by acting like a natural ACE inhibitor, it has antioxidant effects, and more This is the quick version—check the deep dive letter for the nuance and limitations.
#Nattokinase #Atherosclerosis #HeartHealth #CIMT #BloodPressure #VascularHealth #CardioScience #StayCurious #MetabolicHealth
LINK: open.substack.com/pub/staycuriousmetabolism/p/nattokinase-the-heart-health-supplement?r=40ekz2&utm_campaign=post&utm_medium=web&showWelcomeOnShare=true
Nattokinase is trending—but what is it, and can it actually impact atherosclerosis? In one study with over 1,000 participants taking 10,800 units daily for a year, researchers reported a 21.7% reduction in atherosclerosis measured by carotid intima-media thickness (CIMT), an ultrasound-based marker of arterial wall thickening. The results are interesting—and the mechanisms are too: nattokinase may support blood pressure by acting like a natural ACE inhibitor, it has antioxidant effects, and more This is the quick version—check the deep dive letter for the nuance and limitations.
#Nattokinase #Atherosclerosis #HeartHealth #CIMT #BloodPressure #VascularHealth #CardioScience #StayCurious #MetabolicHealth
