Matteson Reaction Mechanism | Organic Chemistry @OrganicMechanismsChannel

Uploaded August 2021 | Updated September 2026, 1 week ago

The mechanism for a Matteson Reaction which involves a homologation of a boronate compound using halocarbanions. ZnCl2 is used as a Lewis acid in order to stabilize the intermediate. In addition, the coordination of the Zn to chlorine of the added halocarbanion is likely pulling the electrons of the chlorine in order to make it a better leaving group and therefore make the reaction progress forward.

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