Gewald Aminothiophene Synthesis Mechanism | Organic Chemistry @OrganicMechanismsChannel

Uploaded November 2023 | Updated September 2026, 2 weeks ago

The mechanism for a Gewals aminothiophene synthesis which involves the base-promoted aminothiophene formation from a ketone, α-active methylene nitrile, and elemental sulfur.

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Gewald Aminothiophene Synthesis Mechanism | Organic Chemistry