Uploaded August 2026 | Updated September 2026, 2 weeks ago

---

Deep dive here: staycuriousmetabolism.substack.com/p/are-we-close-to-unlocking-the-secret?r=40ekz2

Across three controlled human trials, low-protein diets with 9% Cal from protein caused a roughly 20% increase in total energy expenditure. One answer to this weird result might the microbiome. Subsequent experiments identified a four-microbe combination linked to thermogenic fat activity and found that it increased calorie burning in animals. For the full mechanisms, limitations, and nuance, watch the long-form breakdown linked above.

#GutMicrobiome #MetabolicHealth #GutHealth #Thermogenesis #Probiotics #NutritionScience #StayCurious