Uploaded September 2018 | Updated September 2026, 2 weeks ago
This video illustrates the basic principles of signal transduction mechanisms mediated by membrane-bound receptors by focusing on how cholera toxin works on a cellular level to disrupt G-protein signaling, and how this in turn can lead to diarrhea, dehydration, and even death.
This video was created by Shake Karapetyan and Chuan Chang, undergraduate students at New York University Abu Dhabi, as part of an introductory biology course taught by Dr. Kristen Sadler Edepli (Associate Professor at NYU Abu Dhabi) and Mona Kalmouni (Associate Instructor at NYU Abu Dhabi). It is part of our "Student Sketches" series, featuring videos created by students in conjunction with university and high school courses. See the full post for more info and related resources: sciencesketches.org/single-post/2018/09/16/How-does-cholera-make-people-sick
This video illustrates the basic principles of signal transduction mechanisms mediated by membrane-bound receptors by focusing on how cholera toxin works on a cellular level to disrupt G-protein signaling, and how this in turn can lead to diarrhea, dehydration, and even death.
This video was created by Shake Karapetyan and Chuan Chang, undergraduate students at New York University Abu Dhabi, as part of an introductory biology course taught by Dr. Kristen Sadler Edepli (Associate Professor at NYU Abu Dhabi) and Mona Kalmouni (Associate Instructor at NYU Abu Dhabi). It is part of our "Student Sketches" series, featuring videos created by students in conjunction with university and high school courses. See the full post for more info and related resources: sciencesketches.org/single-post/2018/09/16/How-does-cholera-make-people-sick






![Designing a self-propelled vesicle inspired by a bacterial swimmer
We present an original design for a self-propelling lipid bilayer vesicle using a DNA origami rotary motor, powered by transmembrane water flow[1] generated via photoactivable sodium pumps[2] and mimicking bacterial locomotion with a rigid helical flagella.
We have built a numerical model to assess the compatibility between the elements of the system and the viability of its structure and function. From this model, we have identified the limitations of the current design and proposed additional functions to consider for future development.
This video was created by Emma Brix, a student in the Cell Physics Master program at the University of Strasbourg.
Related resources:
[1] X. Shi, A. K. Pumm, C. Maffeo, et al., A dna turbine powered by a transmembrane potential
across a nanopore, Nature Nanotechnology 19, 338 (2024), https://doi.org/10.1038/s41565-023-
01527-8
[2] Y. V. Bertsova, A. V. Bogachev, and V. P. Skulachev, Proteorhodopsin from dokdonia sp. pro95 is a light-driven na+-pump, Biochemistry (Moscow) 80, 449 (2015),
https://doi.org/10.1134/S0006297915040082 Designing a self-propelled vesicle inspired by a bacterial swimmer](https://i.ytimg.com/vi/bsNcls_gKms/mqdefault.jpg)



