Uploaded August 2026 | Updated September 2026, 2 weeks ago

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In this Huberman Lab Essentials episode, my guest is Dr. Chris Palmer, MD, a board-certified psychiatrist and Assistant Professor of Psychiatry at Harvard Medical School. We explain how nutrition and metabolism directly affect mental health, including the biological mechanisms underlying these effects. We also discuss how carbohydrate restriction, ketogenic diets and fasting can improve mood, energy, and, in some cases, treatment-resistant psychiatric conditions.

Show notes: go.hubermanlab.com/it2boBG

Watch more Huberman Lab Essentials: youtube.com/playlist?list=PLPNW_gerXa4OGNy1yE-W9IX-tPu-tJa7S&si=a1_sA7rUT-fE0OM5

Huberman Lab
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Dr. Chris Palmer
Website: chrispalmermd.com
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Timestamps
00:00:00 Chris Palmer
00:00:20 Personal Story, Nutrition & Mental Health
00:05:28 Treatment-Resistant Mental Disorders & Low-Carbohydrate Diet
00:07:32 Ketogenic Diet & Schizophrenia Success Story
00:11:01 Nutrition for Mental Disorders, Ketosis, Highly Processed Foods
00:13:55 Epilepsy & Ketogenic Diet, Fasting; Mitochondrial Benefits
00:19:54 Mitochondria Functions, Mental Disorders
00:25:44 Mitophagy, Autophagy, Longevity & Calorie Restriction
00:30:51 Carbohydrate Restriction, Depression Treatment
00:33:49 Acknowledgements

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