Uploaded November 2025 | Updated September 2026, 1 week ago
“I eat a mountain of salt… and my blood pressure is normal.”
No, not genetics — metabolic context.
Sodium is essential. Whether salt helps or harms depends on your metabolic state. If you’re lean and insulin-sensitive, hormones like leptin (from fat tissue) and neural/kidney signaling can handle sodium very differently than in insulin resistance or obesity.
In this short, Nick Norwitz MD PhD explains why salt isn’t “good” or “bad” in isolation, and why individual context (metabolic health, body composition, history, meds) should shape your approach.
#salt #sodium #bloodpressure #hypertension #metabolichealth #leptin #kidneys #nutrition #nicknorwitz #healthscience #context #nuance #staycurious
“I eat a mountain of salt… and my blood pressure is normal.”
No, not genetics — metabolic context.
Sodium is essential. Whether salt helps or harms depends on your metabolic state. If you’re lean and insulin-sensitive, hormones like leptin (from fat tissue) and neural/kidney signaling can handle sodium very differently than in insulin resistance or obesity.
In this short, Nick Norwitz MD PhD explains why salt isn’t “good” or “bad” in isolation, and why individual context (metabolic health, body composition, history, meds) should shape your approach.
#salt #sodium #bloodpressure #hypertension #metabolichealth #leptin #kidneys #nutrition #nicknorwitz #healthscience #context #nuance #staycurious


![Can Fiber Damage Your Liver?
Link: https://open.substack.com/pub/staycuriousmetabolism/p/fiber-is-good-for-you-is-lazy-s[…]kz2&utm_campaign=post&utm_medium=web&showWelcomeOnShare=true
We’re told fiber is always good—but that’s not the full story. A landmark randomized controlled trial from Stanford tested different fiber types and found that one common fiber, when taken at high doses, significantly increased ALT, a marker of liver injury, in a subset of people. The effect was large enough that researchers stopped the study early for safety concerns.
At lower doses, the same fiber may improve insulin sensitivity and reduce fatty liver, highlighting a key takeaway in nutrition science: dose and individual response matter. This isn’t about fear—it’s about context over dogma.
#Fiber #LiverHealth #NutritionScience #MetabolicHealth #InsulinResistance #FattyLiver #Stanford #RCT #HealthScience #PrecisionNutrition #MedicalEducation #StayCurious Can Fiber Damage Your Liver?](https://i.ytimg.com/vi/HLfFCjEETCY/mqdefault.jpg)







