Brain boost with selenium? @TheSheekeyScienceShow
Brain boost with selenium?  @TheSheekeyScienceShow
Uploaded February 2022 | Updated September 2026, 2 weeks ago
Exercise in general has been known to have neurogenesis-enhancing effects. But how exactly? Well, it is commonly known exercise results in the systemic release of many factors into the blood which could be sensed by neural stem cells in the brain. The question is determining which of these factors are important and relevant to this event.

This brings us onto selenium. Selenium is an essential element you get through your diet from brazil nuts, tuna, eggs, sunflower seeds and oysters. Selenium gets incorporated into proteins as selenocysteine and these proteins are involved in redox regulation and development.

A recent study has brought these two topics together showing that exercise induces selenoprotein p in the blood plasma and this can promote neurogenesis in the hippocampus of the brain. Alternatively to exercise, selenium supplementation in mice also worked and improved spatial memory. But, you might want to be careful that your selenium levels do not get too high...

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TIMESTAMPS
Intro - 00:00
Selenium - 00:17
Exercise - 02:00
Brain boost by selenium? - 02:45
Goldilocks effect - 05:45

REFERENCES:
Selenium Deficiency Is Associated with Pro-longevity Mechanisms - doi.org/10.1016/j.celrep.2019.05.001
Selenium mediates exercise-induced adult neurogenesis and reverses learning deficits induced by hippocampal injury and aging - doi.org/10.1016/j.cmet.2022.01.005
Widely available supplement may explain brain boost from exercise - science.org/content/article/widely-available-supplement-may-explain-brain-boost-exercise

Please note that The Sheekey Science Show is distinct from Eleanor Sheekey's teaching and research roles at the University of Cambridge. The information provided in this show is not medical advice, nor should it be taken or applied as a replacement for medical advice. The Sheekey Science Show and guests assume no liability for the application of the information discussed.

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Brain boost with selenium?

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