Uploaded July 2025 | Updated September 2026, 2 weeks ago

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🧬 In this episode of The Sheekey Science Show, I sit down with Aaron Edwards, co-founder and CEO of KiraGen Bio, to explore how his company is revolutionizing cancer treatment through multiplex gene editing and AI-powered drug discovery.

Aaron brings over a decade of experience in cellular immunotherapy, having led CAR-T and TCR-T advancements at Beam Therapeutics and other top biotech companies. With a Harvard MS/MBA, he's now pioneering next-generation cell therapies that could transform how we treat solid tumors, particularly glioblastoma—one of the most aggressive brain cancers.

🔬 WHAT YOU'LL LEARN:
• Why cancer evades our immune system and how CAR-T therapy works
• The challenges of treating solid tumors vs. blood cancers
• How gene editing creates "off-the-shelf" therapies
• KiraGen's AI platform for optimizing drug combinations
• The unique advantages of Boston's biotech ecosystem
• Practical advice for aspiring biotech entrepreneurs

🧪 ABOUT AARON EDWARDS:
Aaron is co-founder and CEO of KiraGen Bio, a company developing multiplex-edited CAR-T cell therapies for cancer treatment. Previously, he worked at Beam Therapeutics and holds an MS/MBA from Harvard University.
KiraGen Bio: kiragenbio.com

Find me on Twitter - twitter.com/eleanorsheekey

Support the channel:
• PayPal - paypal.me/sheekeyscience?country.x=GB&locale.x=en_GB
• Patreon - patreon.com/TheSheekeyScienceShow

⏰ TIMESTAMPS:
00:00 Introduction to Aaron Edwards & Kiragen Bio
01:30 Why Cancer Evades the Immune System
04:30 CAR-T Cell Therapy Explained
11:00 Conquering Solid Tumors & Glioblastoma
20:00 Gene Editing & Off-the-Shelf Therapies
27:00 AI-Powered Drug Discovery Platform
38:00 Boston Biotech Scene & Founder Advice

🔬 RELATED TOPICS: #biotech #CAR-T #geneEditing #cancerResearch #immunotherapy #AI #biotechStartup #glioblastoma #cellTherapy #precisionMedicine

⚠️ DISCLAIMER:
Please note that The Sheekey Science Show is distinct from Eleanor Sheekey's teaching and research roles. The information provided in this show is not medical advice, nor should it be taken or applied as a replacement for medical advice. The Sheekey Science Show and guests assume no liability for the application of the information discussed.

Icons in intro: "freepik.com/free-photos-vectors/background" Background vector created by freepik - freepik.com