The Sheekey Science Show | Are we in a fertility crisis? @TheSheekeyScienceShow | Uploaded November 2022 | Updated October 2024, 4 days ago.
Last month, the global population hit 8 billion people. Now, like me, that is a number i can say, but cannot really comprehend. It’s big. Basically. And the number of people on the planet are projected to keep growing to 9.7 B by 2050 and 10.4B by the end of the century. But, the rate of population growth is declining.
Now, there are obviously many reasons for this, but one factor that comes into this is the trends of declining fertility. Last week, a meta-analysis study showed that sperm count is declining. But why is this happening and what can be done about it?
Find me on Twitter - twitter.com/EleanorSheekey
Support the channel
through PayPal - paypal.me/sheekeyscience?country.x=GB&locale.x=en_GB
through Patreon - patreon.com/TheSheekeyScienceShow
TIMESTAMPS:
Intro - 00:00
Fertility - 01:11
Sperm count decline - 01:45
Genetics - 04:00
Epigenetics - 05:00
Environment - 05:55
Outlook - 06:50
References:
UN data - un.org/development/desa/pd/sites/un.org.development.desa.pd/files/wpp2022_summary_of_results.pdf
Skakkebæk, N.E., Lindahl-Jacobsen, R., Levine, H. et al. Environmental factors in declining human fertility. Nat Rev Endocrinol 18, 139–157 (2022). doi.org/10.1038/s41574-021-00598-8
Hagai Levine, Niels Jørgensen, Anderson Martino-Andrade, Jaime Mendiola, Dan Weksler-Derri, Maya Jolles, Rachel Pinotti, Shanna H Swan, Temporal trends in sperm count: a systematic review and meta-regression analysis of samples collected globally in the 20th and 21st centuries, Human Reproduction Update, 2022;, dmac035, doi.org/10.1093/humupd/dmac035
Body fluid concentrations of bisphenol A and their association with in vitro fertilization outcomes - doi.org/10.1080/14647273.2019.1612104
Exposure to modern, widespread environmental endocrine disrupting chemicals and their effect on the reproductive potential of women: an overview of current epidemiological evidence - doi.org/10.1080/14647273.2017.1358828
Persistent environmental endocrine-disrupting chemicals in ovarian follicular fluid and in vitro fertilization treatment outcome in women - doi.org/10.1080/03009734.2020.1727073
Xu, H., Wang, X., Wang, Z. et al. MicroRNA expression profile analysis in sperm reveals hsa-mir-191 as an auspicious omen of in vitro fertilization. BMC Genomics 21, 165 (2020). doi.org/10.1186/s12864-020-6570-8
Ruth, K.S., Day, F.R., Hussain, J. et al. Genetic insights into biological mechanisms governing human ovarian ageing. Nature 596, 393–397 (2021). doi.org/10.1038/s41586-021-03779-7
Please note that The Sheekey Science Show is distinct from Eleanor Sheekey's teaching and research roles at the University of Cambridge. The information provided in this show is not medical advice, nor should it be taken or applied as a replacement for medical advice. The Sheekey Science Show and guests assume no liability for the application of the information discussed.
Icons in intro; "freepik.com/free-photos-vectors/background"Background vector created by freepik - freepik.com
Last month, the global population hit 8 billion people. Now, like me, that is a number i can say, but cannot really comprehend. It’s big. Basically. And the number of people on the planet are projected to keep growing to 9.7 B by 2050 and 10.4B by the end of the century. But, the rate of population growth is declining.
Now, there are obviously many reasons for this, but one factor that comes into this is the trends of declining fertility. Last week, a meta-analysis study showed that sperm count is declining. But why is this happening and what can be done about it?
Find me on Twitter - twitter.com/EleanorSheekey
Support the channel
through PayPal - paypal.me/sheekeyscience?country.x=GB&locale.x=en_GB
through Patreon - patreon.com/TheSheekeyScienceShow
TIMESTAMPS:
Intro - 00:00
Fertility - 01:11
Sperm count decline - 01:45
Genetics - 04:00
Epigenetics - 05:00
Environment - 05:55
Outlook - 06:50
References:
UN data - un.org/development/desa/pd/sites/un.org.development.desa.pd/files/wpp2022_summary_of_results.pdf
Skakkebæk, N.E., Lindahl-Jacobsen, R., Levine, H. et al. Environmental factors in declining human fertility. Nat Rev Endocrinol 18, 139–157 (2022). doi.org/10.1038/s41574-021-00598-8
Hagai Levine, Niels Jørgensen, Anderson Martino-Andrade, Jaime Mendiola, Dan Weksler-Derri, Maya Jolles, Rachel Pinotti, Shanna H Swan, Temporal trends in sperm count: a systematic review and meta-regression analysis of samples collected globally in the 20th and 21st centuries, Human Reproduction Update, 2022;, dmac035, doi.org/10.1093/humupd/dmac035
Body fluid concentrations of bisphenol A and their association with in vitro fertilization outcomes - doi.org/10.1080/14647273.2019.1612104
Exposure to modern, widespread environmental endocrine disrupting chemicals and their effect on the reproductive potential of women: an overview of current epidemiological evidence - doi.org/10.1080/14647273.2017.1358828
Persistent environmental endocrine-disrupting chemicals in ovarian follicular fluid and in vitro fertilization treatment outcome in women - doi.org/10.1080/03009734.2020.1727073
Xu, H., Wang, X., Wang, Z. et al. MicroRNA expression profile analysis in sperm reveals hsa-mir-191 as an auspicious omen of in vitro fertilization. BMC Genomics 21, 165 (2020). doi.org/10.1186/s12864-020-6570-8
Ruth, K.S., Day, F.R., Hussain, J. et al. Genetic insights into biological mechanisms governing human ovarian ageing. Nature 596, 393–397 (2021). doi.org/10.1038/s41586-021-03779-7
Please note that The Sheekey Science Show is distinct from Eleanor Sheekey's teaching and research roles at the University of Cambridge. The information provided in this show is not medical advice, nor should it be taken or applied as a replacement for medical advice. The Sheekey Science Show and guests assume no liability for the application of the information discussed.
Icons in intro; "freepik.com/free-photos-vectors/background"Background vector created by freepik - freepik.com
