Uploaded December 2023 | Updated September 2026, 1 week ago
Bon Q. Trinh, PhD, Assistant Professor, Department of Pathology
Transcript:
Most of our human genome do not code for protein and is it called non-coding DNA? It will also consider an important. However, with advances in whole genome sequencing technology, it become clear that the genomic material contain many hidden charm. They include DNA proprietary element and non-coding RNA that control fundamental biological and pathological processes.
I am Bon Q. Trinh and I am an assistant professor in experimental pathology at the University of Virginia School of Medicine. My group employs experimental and computational approaches to understand how Biomolecule regulates gene expression at the chromatin level during normal blood cell development and cancer.
We have demonstrated the important roles of a bimolecular interplay in the control of 3D chromatin architecture. In my life cells, these immune cells play a crucial role in our body defense against infection. But abnormality during their normal development either cause a fatal breast cancer or acute myeloid leukemia. We are investigating epigenetic gene regulation in drug resistance and in the disease in these immune cells to become either pro or anti-tumor.
The Manning Institute of Biotechnology could provide valuable support in our efforts to translate our basic research findings to good critical application.
Bon Q. Trinh, PhD, Assistant Professor, Department of Pathology
Transcript:
Most of our human genome do not code for protein and is it called non-coding DNA? It will also consider an important. However, with advances in whole genome sequencing technology, it become clear that the genomic material contain many hidden charm. They include DNA proprietary element and non-coding RNA that control fundamental biological and pathological processes.
I am Bon Q. Trinh and I am an assistant professor in experimental pathology at the University of Virginia School of Medicine. My group employs experimental and computational approaches to understand how Biomolecule regulates gene expression at the chromatin level during normal blood cell development and cancer.
We have demonstrated the important roles of a bimolecular interplay in the control of 3D chromatin architecture. In my life cells, these immune cells play a crucial role in our body defense against infection. But abnormality during their normal development either cause a fatal breast cancer or acute myeloid leukemia. We are investigating epigenetic gene regulation in drug resistance and in the disease in these immune cells to become either pro or anti-tumor.
The Manning Institute of Biotechnology could provide valuable support in our efforts to translate our basic research findings to good critical application.
