Uploaded December 2025 | Updated September 2026, 1 week ago
Treating Knee Bone Marrow Lesions with the IOBP® Procedure: Technique Demonstration
In this comprehensive surgical demonstration, Dr. Rajit Saluja (Franklin, WI) showcases the IntraOsseous BioPlasty® (IOBP®) procedure for treating bone marrow lesions in the knee. This minimally invasive technique combines AlloSync™ Pure demineralized bone matrix with Angel® concentrated platelet-rich plasma derived from bone marrow aspirate (cPRP from BMA) to address these challenging defects. Dr. Saluja provides a step-by-step walkthrough of the procedure, from initial bone marrow aspiration to the final fluoroscopic confirmation of successful lesion filling.
Procedure Overview
Dr. Rajit Saluja demonstrates the complete IOBP® procedure for treating a bone marrow edema lesion in the medial femoral condyle. The process begins with obtaining approximately 60cc of bone marrow aspirate from the posterior superior iliac spine, which is then processed using the Arthrex Angel® system to create a concentrated solution. This 5cc concentrate is mixed with 5cc of AlloSync™ (demineralized bone matrix) and 1cc of contrast agent for visualization during the procedure.
The preparation involves dividing the mixture into 5 one-cc syringes, which Dr. Saluja prefers for cases involving multiple lesions as it allows for easier allocation of material based on lesion size. After completing the arthroscopic portion of the procedure, including meniscal debridement, fluoroscopic guidance is used to identify the entry point for the injection.
Using the IOBP closed-tip delivery cannula, which Dr. Saluja selects specifically to enable more circumferential filling of the lesion, the mixture is injected parallel to the joint line. The technique includes gradual impaction of the delivery system, rotation of the device to fill anterior and posterior portions of the lesion, and progressive withdrawal of the system while continuing to inject. Fluoroscopic imaging confirms complete filling of the bone marrow lesion from multiple angles.
Technological Components of the Procedure
The procedure showcased in this video integrates several specialized Arthrex technologies:
- **IOBP® Procedure**: A minimally invasive technique designed specifically for treating bone marrow lesions
- **AlloSync™ Pure**: Demineralized bone matrix that serves as a scaffold for the biological treatment
- **Angel® System**: Used to process and concentrate the bone marrow aspirate into therapeutic cPRP
- **IOBP Closed-Tip Delivery Cannula**: Designed for optimal circumferential filling of lesions
This combination of technologies demonstrates Arthrex's comprehensive approach to addressing challenging knee pathologies through minimally invasive biological interventions.
Clinical Context and Application
Bone marrow lesions represent significant challenges in orthopedic practice, often associated with pain and potential progression of joint degeneration. The IOBP® procedure offers a targeted biological approach that aims to address the underlying pathology rather than simply managing symptoms. By directly delivering a mixture of demineralized bone matrix and concentrated bone marrow aspirate to the lesion site, this technique harnesses the regenerative potential of the patient's own biology.
For more detailed information about this technique and related technologies, visit: arthrex.info/3YvZNbq
Follow Arthrex for More Educational Content
📱 Follow Arthrex on:
LinkedIn: linkedin.com/company/arthrex
Facebook: facebook.com/Arthrex
Instagram: instagram.com/arthrex_inc
X: https://x.com/arthrex
Arthrex is a global leader in orthopedic surgical innovation, dedicated to advancing minimally invasive techniques and medical education. Our mission is to help surgeons treat their patients better by providing cutting-edge products, expert training, and comprehensive resources for orthopedic procedures, including sports medicine, joint preservation, and trauma care.
#BoneMarrowLesions #IOBP #ArthroscopicSurgery #KneePreservation
Treating Knee Bone Marrow Lesions with the IOBP® Procedure: Technique Demonstration
In this comprehensive surgical demonstration, Dr. Rajit Saluja (Franklin, WI) showcases the IntraOsseous BioPlasty® (IOBP®) procedure for treating bone marrow lesions in the knee. This minimally invasive technique combines AlloSync™ Pure demineralized bone matrix with Angel® concentrated platelet-rich plasma derived from bone marrow aspirate (cPRP from BMA) to address these challenging defects. Dr. Saluja provides a step-by-step walkthrough of the procedure, from initial bone marrow aspiration to the final fluoroscopic confirmation of successful lesion filling.
Procedure Overview
Dr. Rajit Saluja demonstrates the complete IOBP® procedure for treating a bone marrow edema lesion in the medial femoral condyle. The process begins with obtaining approximately 60cc of bone marrow aspirate from the posterior superior iliac spine, which is then processed using the Arthrex Angel® system to create a concentrated solution. This 5cc concentrate is mixed with 5cc of AlloSync™ (demineralized bone matrix) and 1cc of contrast agent for visualization during the procedure.
The preparation involves dividing the mixture into 5 one-cc syringes, which Dr. Saluja prefers for cases involving multiple lesions as it allows for easier allocation of material based on lesion size. After completing the arthroscopic portion of the procedure, including meniscal debridement, fluoroscopic guidance is used to identify the entry point for the injection.
Using the IOBP closed-tip delivery cannula, which Dr. Saluja selects specifically to enable more circumferential filling of the lesion, the mixture is injected parallel to the joint line. The technique includes gradual impaction of the delivery system, rotation of the device to fill anterior and posterior portions of the lesion, and progressive withdrawal of the system while continuing to inject. Fluoroscopic imaging confirms complete filling of the bone marrow lesion from multiple angles.
Technological Components of the Procedure
The procedure showcased in this video integrates several specialized Arthrex technologies:
- **IOBP® Procedure**: A minimally invasive technique designed specifically for treating bone marrow lesions
- **AlloSync™ Pure**: Demineralized bone matrix that serves as a scaffold for the biological treatment
- **Angel® System**: Used to process and concentrate the bone marrow aspirate into therapeutic cPRP
- **IOBP Closed-Tip Delivery Cannula**: Designed for optimal circumferential filling of lesions
This combination of technologies demonstrates Arthrex's comprehensive approach to addressing challenging knee pathologies through minimally invasive biological interventions.
Clinical Context and Application
Bone marrow lesions represent significant challenges in orthopedic practice, often associated with pain and potential progression of joint degeneration. The IOBP® procedure offers a targeted biological approach that aims to address the underlying pathology rather than simply managing symptoms. By directly delivering a mixture of demineralized bone matrix and concentrated bone marrow aspirate to the lesion site, this technique harnesses the regenerative potential of the patient's own biology.
For more detailed information about this technique and related technologies, visit: arthrex.info/3YvZNbq
Follow Arthrex for More Educational Content
📱 Follow Arthrex on:
LinkedIn: linkedin.com/company/arthrex
Facebook: facebook.com/Arthrex
Instagram: instagram.com/arthrex_inc
X: https://x.com/arthrex
Arthrex is a global leader in orthopedic surgical innovation, dedicated to advancing minimally invasive techniques and medical education. Our mission is to help surgeons treat their patients better by providing cutting-edge products, expert training, and comprehensive resources for orthopedic procedures, including sports medicine, joint preservation, and trauma care.
#BoneMarrowLesions #IOBP #ArthroscopicSurgery #KneePreservation
