Patrick Kelly | The History of Phage Therapy @PatKellyTeaches | Uploaded February 2024 | Updated October 2024, 57 minutes ago.
Phage therapy uses viruses called bacteriophages to destroy specific bacteria. Scientists are hopeful that they could become a tool to fight antibiotic-resistant germs. In this video, Patrick Kelly guides you through the history of phage therapy's development.
☠️NONE OF THE INFORMATION IN THIS VIDEO SHOULD BE USED AS MEDICAL ADVICE OR OPINION. IT IS FOR GENERAL EDUCATION AND ENTERTAINMENT☠️
🔗 L I N K S 🔗
📱Instagram: instagram.com/patkellyteaches
🐦Twitter: twitter.com/PatKellyTeaches
💰Patreon: patreon.com/corporis
🔬Main channel: youtube.com/corporis
📚My favorite books docs.google.com/document/d/1wuG-8EiF2lMbFdEG-9k1qi1d1KZAdGK1o41o7SYed_k/edit?usp=sharing
🔑 P A T R O N S 🔑
Oxytocin Tier: Mike W | Joanne K | Jim C Jr. | Sal F | Jody O | Ansel K
Growth Hormone Tier: Dane M | Brendan P | Brandon K | Kathy K | Pia K | Joe B | Mindi F | Ansel K | Michael G | Brian B | Eileen H | Jonathan G | Waffles the Dog | Brian T | Brian H | Michael R | Karen S | Sarah B | Robin B | Jacob S | Hyeon-Seo | Drake W | Pranav M | Paul | Lucy F | Lucie C | Huynhy | elnombre91 | Alcedo | Magmania | Josef K | Kyle K | Dabrick B | Robert M | Kristal C
📜 S O U R C E S 📜
The Good Virus by Tom Ireland amazon.com/Good-Virus-Amazing-Forgotten-Promise/dp/1324050837?&_encoding=UTF8&tag=corporis-20&linkCode=ur2&linkId=aa68d4d0cf5456aef18c11eebb8a07d0&camp=1789&creative=9325
The Perfect Predator by Stephanie Strathdee amazon.com/Perfect-Predator-Scientists-Husband-Superbug/dp/0316418110/ref=sr_1_1?crid=39J5FPAXZ35OB&keywords=the+perfect+predator&qid=1706799668&s=books&sprefix=the+perfect+preda%252Cstripbooks%252C212&sr=1-1&_encoding=UTF8&tag=corporis-20&linkCode=ur2&linkId=70fed613c532aa9e78d3aabf42496ea2&camp=1789&creative=9325
Annotated script here: patreon.com/posts/phage-video-is-97650618
Bacteriophage Therapy of Bacterial Infections: The Rediscovered Frontier (2021)
mdpi.com/1424-8247/14/1/34
Standardized bacteriophage purification for personalized phage therapy (2020) nature.com/articles/s41596-020-0346-0
Phage Therapy: A Renewed Approach to Combat Antibiotic-Resistant Bacteria (2019) cell.com/cell-host-microbe/pdf/S1931-3128(19)30052-6.pdf
Phage Cocktail Development for Bacteriophage Therapy (2021) ncbi.nlm.nih.gov/pmc/articles/PMC8541335
Hankin paper (1896) archive.org/details/annalesdelinstit10inst/page/522/mode/1up?view=theater tandfonline.com/doi/pdf/10.4161/bact.1.3.16736?needAccess=true
A Brief History of Shigella (2018) ncbi.nlm.nih.gov/pmc/articles/PMC8559768
An Early History of Phage Therapy in the United States (2021) ncbi.nlm.nih.gov/pmc/articles/PMC8231696
Bacteriophage prehistory (2011) ncbi.nlm.nih.gov/pmc/articles/PMC3225782
The virus in the rivers: histories and antibiotic afterlives of the bacteriophage at the sangam in Allahabad (2020) royalsocietypublishing.org/doi/full/10.1098/rsnr.2020.0019
Bacteriophage Therapy (2001) ncbi.nlm.nih.gov/pmc/articles/PMC90351
The Third Age of Phage (2005) journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.0030182
An invisible microbe that is antagonistic to the dysentery bacillus (1917) by F. d’Herelle — translation of original French sciencedirect.com/science/article/pii/S0923250807001507?via%3Dihub
Le bacteriophage (1921) by D’Herelle archive.org/details/lebactriophages00hrgoog/page/n7/mode/2up
Bacteriophage and Staph skin infections (1921) https://gallica.bnf.fr/ark:/12148/bpt6k6541609m/f479.item
Cholera and Plague in India: The Bacteriophage Inquiry of 1927-1936 web.archive.org/web/20170811194935id_/sites.ualberta.ca/~pukatzki/labpage/Lab_News/Entries/2010/11/14_Phage_Therapy_files/The%20Bacteriophage%20Inquiry.pdf
The Adoption and Survival of Bacteriophage Therapy in the USSR (2018) academic.oup.com/jhmas/article/73/4/385/5128730
The prospect for bacteriophage therapy in Western medicine (2003) nature.com/articles/nrd1111.pdf
An interview with Elizabeth Kutter ncbi.nlm.nih.gov/pmc/articles/PMC9041451
IMAGES
Portrait of Steffanie A. Strathdee by Scott Lafee for Triton Magazine. CC-BY-SA 4.0 en.wikipedia.org/wiki/Steffanie_A._Strathdee#/media/File:Strathdee_Portrait.png
creativecommons.org/licenses/by-sa/4.0
Intralytix Headquarters by Rayford Payne. CC-BY-SA 4.0
upload.wikimedia.org/wikipedia/commons/5/5a/Intralytix_Exterior_Spring.jpg
youtube.com/watch?v=qCzCj4gQWLk&t=4s
💻 C O N T A C T 💻
patkellyteaches [at] gmail.com
⌛T I M E S T A M P S ⌛
0:00 intro
0:48 What is a Phage
2:00 Ernest Hankin
5:18 Fredrick Twort
6:50 Felix d’Herelle
16:52 Phage Therapy in the Soviet Union
22:19 Phage Therapy in the USA
25:16 Challenges to phage therapy
28:09 Why are people hopeful?
#historyofmedicine #medicalhistory
Phage therapy uses viruses called bacteriophages to destroy specific bacteria. Scientists are hopeful that they could become a tool to fight antibiotic-resistant germs. In this video, Patrick Kelly guides you through the history of phage therapy's development.
☠️NONE OF THE INFORMATION IN THIS VIDEO SHOULD BE USED AS MEDICAL ADVICE OR OPINION. IT IS FOR GENERAL EDUCATION AND ENTERTAINMENT☠️
🔗 L I N K S 🔗
📱Instagram: instagram.com/patkellyteaches
🐦Twitter: twitter.com/PatKellyTeaches
💰Patreon: patreon.com/corporis
🔬Main channel: youtube.com/corporis
📚My favorite books docs.google.com/document/d/1wuG-8EiF2lMbFdEG-9k1qi1d1KZAdGK1o41o7SYed_k/edit?usp=sharing
🔑 P A T R O N S 🔑
Oxytocin Tier: Mike W | Joanne K | Jim C Jr. | Sal F | Jody O | Ansel K
Growth Hormone Tier: Dane M | Brendan P | Brandon K | Kathy K | Pia K | Joe B | Mindi F | Ansel K | Michael G | Brian B | Eileen H | Jonathan G | Waffles the Dog | Brian T | Brian H | Michael R | Karen S | Sarah B | Robin B | Jacob S | Hyeon-Seo | Drake W | Pranav M | Paul | Lucy F | Lucie C | Huynhy | elnombre91 | Alcedo | Magmania | Josef K | Kyle K | Dabrick B | Robert M | Kristal C
📜 S O U R C E S 📜
The Good Virus by Tom Ireland amazon.com/Good-Virus-Amazing-Forgotten-Promise/dp/1324050837?&_encoding=UTF8&tag=corporis-20&linkCode=ur2&linkId=aa68d4d0cf5456aef18c11eebb8a07d0&camp=1789&creative=9325
The Perfect Predator by Stephanie Strathdee amazon.com/Perfect-Predator-Scientists-Husband-Superbug/dp/0316418110/ref=sr_1_1?crid=39J5FPAXZ35OB&keywords=the+perfect+predator&qid=1706799668&s=books&sprefix=the+perfect+preda%252Cstripbooks%252C212&sr=1-1&_encoding=UTF8&tag=corporis-20&linkCode=ur2&linkId=70fed613c532aa9e78d3aabf42496ea2&camp=1789&creative=9325
Annotated script here: patreon.com/posts/phage-video-is-97650618
Bacteriophage Therapy of Bacterial Infections: The Rediscovered Frontier (2021)
mdpi.com/1424-8247/14/1/34
Standardized bacteriophage purification for personalized phage therapy (2020) nature.com/articles/s41596-020-0346-0
Phage Therapy: A Renewed Approach to Combat Antibiotic-Resistant Bacteria (2019) cell.com/cell-host-microbe/pdf/S1931-3128(19)30052-6.pdf
Phage Cocktail Development for Bacteriophage Therapy (2021) ncbi.nlm.nih.gov/pmc/articles/PMC8541335
Hankin paper (1896) archive.org/details/annalesdelinstit10inst/page/522/mode/1up?view=theater tandfonline.com/doi/pdf/10.4161/bact.1.3.16736?needAccess=true
A Brief History of Shigella (2018) ncbi.nlm.nih.gov/pmc/articles/PMC8559768
An Early History of Phage Therapy in the United States (2021) ncbi.nlm.nih.gov/pmc/articles/PMC8231696
Bacteriophage prehistory (2011) ncbi.nlm.nih.gov/pmc/articles/PMC3225782
The virus in the rivers: histories and antibiotic afterlives of the bacteriophage at the sangam in Allahabad (2020) royalsocietypublishing.org/doi/full/10.1098/rsnr.2020.0019
Bacteriophage Therapy (2001) ncbi.nlm.nih.gov/pmc/articles/PMC90351
The Third Age of Phage (2005) journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.0030182
An invisible microbe that is antagonistic to the dysentery bacillus (1917) by F. d’Herelle — translation of original French sciencedirect.com/science/article/pii/S0923250807001507?via%3Dihub
Le bacteriophage (1921) by D’Herelle archive.org/details/lebactriophages00hrgoog/page/n7/mode/2up
Bacteriophage and Staph skin infections (1921) https://gallica.bnf.fr/ark:/12148/bpt6k6541609m/f479.item
Cholera and Plague in India: The Bacteriophage Inquiry of 1927-1936 web.archive.org/web/20170811194935id_/sites.ualberta.ca/~pukatzki/labpage/Lab_News/Entries/2010/11/14_Phage_Therapy_files/The%20Bacteriophage%20Inquiry.pdf
The Adoption and Survival of Bacteriophage Therapy in the USSR (2018) academic.oup.com/jhmas/article/73/4/385/5128730
The prospect for bacteriophage therapy in Western medicine (2003) nature.com/articles/nrd1111.pdf
An interview with Elizabeth Kutter ncbi.nlm.nih.gov/pmc/articles/PMC9041451
IMAGES
Portrait of Steffanie A. Strathdee by Scott Lafee for Triton Magazine. CC-BY-SA 4.0 en.wikipedia.org/wiki/Steffanie_A._Strathdee#/media/File:Strathdee_Portrait.png
creativecommons.org/licenses/by-sa/4.0
Intralytix Headquarters by Rayford Payne. CC-BY-SA 4.0
upload.wikimedia.org/wikipedia/commons/5/5a/Intralytix_Exterior_Spring.jpg
youtube.com/watch?v=qCzCj4gQWLk&t=4s
💻 C O N T A C T 💻
patkellyteaches [at] gmail.com
⌛T I M E S T A M P S ⌛
0:00 intro
0:48 What is a Phage
2:00 Ernest Hankin
5:18 Fredrick Twort
6:50 Felix d’Herelle
16:52 Phage Therapy in the Soviet Union
22:19 Phage Therapy in the USA
25:16 Challenges to phage therapy
28:09 Why are people hopeful?
#historyofmedicine #medicalhistory
