Uploaded July 2026 | Updated September 2026, 5 hours ago
You might think the win on a GLP-1 like Ozempic or Mounjaro is the number dropping on your scale, but I need you to ask a better question, not how much you're losing, but what kind. In some studies, 40 to 60% of the weight people lost on these drugs came from lean muscle, not fat, and that's a metabolic loss that costs you your strength and your ability to keep the weight off. These are the most powerful fat-loss tools we've ever had, but a tool without a protocol is just potential. Hit your protein and lift, or you're trading muscle for a number you'll spend years trying to earn back.
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Watch the “Ultimate Human Podcast” every Tuesday & Thursday at 9AM EST:
YouTube: bit.ly/3RPQYX8
Podcasts: bit.ly/3RQftU0
Connect with Gary Brecka
Instagram: bit.ly/3RPpnFs
TikTok: bit.ly/4coJ8fo
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Timestamps
00:00 - Intro of Show
00:22 - Weight loss vs fat loss
00:38 - What GLP-1 does in the body
01:02 - Semaglutide: the first generation
01:28 - Tirzepatide and the dual agonist
01:45 - Retatrutide and 24.2% body weight loss
02:20 - Why each added receptor works
02:38 - The hidden cost: protecting lean muscle
03:05 - 60% of weight loss from muscle
03:35 - The two-part fix: protein and training
04:05 - Protein targets and leucine-rich sources
04:30 - Resistance training and compound lifts
05:00 - Use the medication, do the work
Disclaimer: This podcast is for informational purposes only and does not provide medical advice. It is not intended for diagnosing or treating any health condition. Always consult a licensed healthcare professional before making health or wellness decisions.
Gary Brecka is the owner of Ultimate Human, LLC which operates The Ultimate Human podcast and promotes certain third-party products used by Gary Brecka in his personal health and wellness protocols and daily life and for which Ultimate Human LLC and / or Gary Brecka directly or indirectly holds an economic interest or receives compensation. Accordingly, statements made by Gary Brecka and others (including on The Ultimate Human podcast) may be considered promotional in nature.
You might think the win on a GLP-1 like Ozempic or Mounjaro is the number dropping on your scale, but I need you to ask a better question, not how much you're losing, but what kind. In some studies, 40 to 60% of the weight people lost on these drugs came from lean muscle, not fat, and that's a metabolic loss that costs you your strength and your ability to keep the weight off. These are the most powerful fat-loss tools we've ever had, but a tool without a protocol is just potential. Hit your protein and lift, or you're trading muscle for a number you'll spend years trying to earn back.
CLICK HERE TO BECOME GARYS VIP!: bit.ly/4ai0Xwg
Thank you to our partners
A-GAME: “ULTIMATE15” FOR 15% OFF: bit.ly/4kek1ij
AION: “ULTIMATE10” FOR 10% OFF: bit.ly/4h6KHAD
AIRES: "ULTIMATE20 " FOR 20% OFF: bit.ly/4a3Duze
BAJA GOLD: "ULTIMATE10" FOR 10% OFF: bit.ly/3WSBqUa
BODYHEALTH: “ULTIMATE20” FOR 20% OFF: bit.ly/4e5IjsV
COLD LIFE: THE ULTIMATE HUMAN PLUNGE: bit.ly/4eULUKp
CYMBIOTIKA: "BRECKACYM30" FOR 30% OFF: bit.ly/4tjyluP
GENETIC METHYLATION TEST (UK ONLY): bit.ly/48QJJrk
GENETIC TEST (USA ONLY): bit.ly/3Yg1Uk9
GOPUFF: GET YOUR FAVORITE SNACK!: bit.ly/4obIFDC
H2TABS: “ULTIMATE10” FOR 10% OFF: bit.ly/4hMNdgg
HEALF: 10% OFF YOUR ORDER: bit.ly/41HJg6S
PEPTUAL: “TUH10” FOR 10% OFF: bit.ly/4mKxgcn
SNOOZE: LET’S GET TO SLEEP!: bit.ly/4pt1T6V
WHOOP: JOIN & GET 1 FREE MONTH!: bit.ly/3VQ0nzW
Watch the “Ultimate Human Podcast” every Tuesday & Thursday at 9AM EST:
YouTube: bit.ly/3RPQYX8
Podcasts: bit.ly/3RQftU0
Connect with Gary Brecka
Instagram: bit.ly/3RPpnFs
TikTok: bit.ly/4coJ8fo
X: bit.ly/3Opc8tf
Facebook: bit.ly/464VA1H
LinkedIn: bit.ly/4hH7Ri2
Website: bit.ly/4eLDbdU
Merch: bit.ly/4aBpOM1
Newsletter: bit.ly/47ejrws
Ask Gary: bit.ly/3PEAJuG
Timestamps
00:00 - Intro of Show
00:22 - Weight loss vs fat loss
00:38 - What GLP-1 does in the body
01:02 - Semaglutide: the first generation
01:28 - Tirzepatide and the dual agonist
01:45 - Retatrutide and 24.2% body weight loss
02:20 - Why each added receptor works
02:38 - The hidden cost: protecting lean muscle
03:05 - 60% of weight loss from muscle
03:35 - The two-part fix: protein and training
04:05 - Protein targets and leucine-rich sources
04:30 - Resistance training and compound lifts
05:00 - Use the medication, do the work
Disclaimer: This podcast is for informational purposes only and does not provide medical advice. It is not intended for diagnosing or treating any health condition. Always consult a licensed healthcare professional before making health or wellness decisions.
Gary Brecka is the owner of Ultimate Human, LLC which operates The Ultimate Human podcast and promotes certain third-party products used by Gary Brecka in his personal health and wellness protocols and daily life and for which Ultimate Human LLC and / or Gary Brecka directly or indirectly holds an economic interest or receives compensation. Accordingly, statements made by Gary Brecka and others (including on The Ultimate Human podcast) may be considered promotional in nature.
