PureTarget: Modernize carrier screening with long-read sequencing @PacificBiosciences
PureTarget: Modernize carrier screening with long-read sequencing  @PacificBiosciences
Uploaded December 2025 | Updated September 2026, 1 hour ago
*How can you replace multiple legacy assays with one streamlined workflow?* PureTarget from PacBio offers a powerful, consolidated solution for carrier screening research.

Traditional methods like Southern blots and PCR are often labor-intensive, costly, and fragmented. PureTarget leverages PacBio HiFi sequencing to consolidate 12 difficult genes—including FMR1 and SMN—into a single, scalable, PCR-free panel that integrates seamlessly with your existing lab automation.

*What can you do with PureTarget?*
* Consolidate legacy assays (qPCR, Southern blot, MLPA) into one efficient workflow.
* Target 12 hard-to-sequence genes like FMR1, FXN, and SMN with high precision.
* Scale up to 100,000 samples per year on a single Revio system.
* Automate library prep and analysis using Hamilton scripts and DNANexus pipelines.

*Resources*
* pacb.com/technology/puretarget
* pacb.com/revio

Which legacy assay are you most eager to replace in your lab? *Comment below.*

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#PureTarget #CarrierScreening #HiFiSequencing
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PureTarget: Modernize carrier screening with long-read sequencing

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