Patrick Kelly | Penicillin: From Fleming to the Pharmacy @PatKellyTeaches | Uploaded September 2023 | Updated October 2024, 1 hour ago.
Penicillin's discovery by Alexander Fleming in 1929 gets a lot of hype as the advent of antibiotics. But in reality, Fleming was just one part of the story. A team from Oxford University led by Howard Florey, in partnership with the Northern Lab in the USA brought penicillin production to the world. In this video, Patrick Kelly tells the history of penicillin.
☠️NONE OF THE INFORMATION IN THIS VIDEO SHOULD BE USED AS MEDICAL ADVICE OR OPINION. IT IS FOR GENERAL EDUCATION AND ENTERTAINMENT☠️
🔗 L I N K S 🔗
📱Instagram: instagram.com/patkellyteaches
🐦Twitter: twitter.com/PatKellyTeaches
💰Patreon: patreon.com/corporis
🔬Main channel: youtube.com/corporis
📚My favorite books docs.google.com/document/d/1wuG-8EiF2lMbFdEG-9k1qi1d1KZAdGK1o41o7SYed_k/edit?usp=sharing
🔑 P A T R O N S 🔑
Ron Blumenfeld
Joanne K
Sal F.
Ansel K
Anton
Brandon K
Rourou Y
Brendan P
Dane M
Kristoffer R
Jakub V
Joe B
Karly N
Mindi F
Kathy K
Hyeon-Seo
Jacob S.
Robin B
Sarah B
Carl
Karen S
Michael R
Brian H
Brian T
Waffles the Dog
Silverstar
Robb W
Brian B
Michael G
📜 S O U R C E S 📜
Image attributions and fact checked script can be found here. You do not need to be a Patron to view: patreon.com/posts/penicillin-89784054
Miracle Cure, the Creation of Antibiotics amazon.com/Miracle-Cure-Creation-Antibiotics-Medicine/dp/0525428100?&_encoding=UTF8&tag=corporis-20&linkCode=ur2&linkId=536c2608b02b02e77356edd136b4d016&camp=1789&creative=9325
Science, Government, and the Mass Production of Penicillin by PETER NEUSHUL (1993)
jstor.org/stable/24623264
The Discovery of Penicillin: New Insights After More Than 75 Years of Clinical Use (2017) ncbi.nlm.nih.gov/pmc/articles/PMC5403050
Post- penicillin antibiotics researchgate.net/publication/32886496_Post_penicillin_antibiotics_from_acceptance_to_resistance
Fleming biographies
aai.org/About/History/Notable-Members/Nobel-Laureates/AlexanderFleming
sciencehistory.org/education/scientific-biographies/alexander-fleming
pbs.org/wgbh/aso/databank/entries/bmflem.html
scientificamerican.com/article/penicillin-wasn-rsquo-t-alexander-fleming-rsquo-s-first-major-discovery
ncbi.nlm.nih.gov/pmc/articles/PMC4520913
Fleming’s 1917 Flavine paper
thelancet.com/journals/lancet/article/PIIS0140-6736(01)52126-1/fulltext
Fleming’s WW1 notebook clippings
bl.uk/collection-items/alexander-flemings-notebook-june-1917-1918
Fleming’s 1929 Penicillin paper
ncbi.nlm.nih.gov/pmc/articles/PMC2048009/pdf/brjexppathol00255-0037.pdf
Fleming’s 1932 Lysozyme retrospective in Journal of Royal Society of Medicine
journals.sagepub.com/toc/jrsa/26/2
Fleming BMJ 1941 correspondence
ncbi.nlm.nih.gov/pmc/articles/PMC2162878/pdf/brmedj04059-0024a.pdf
Did Fleming deserve the Nobel? link.springer.com/content/pdf/10.1007/s11948-019-00149-5.pdf
Beta-lactam pharmcology
ncbi.nlm.nih.gov/pmc/articles/PMC5369031
ncbi.nlm.nih.gov/books/NBK554560
sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/beta-lactam-antibiotic
pubs.acs.org/doi/10.1021/ja038445l
ncbi.nlm.nih.gov/pmc/articles/PMC7144564
Florey and Chain biography sciencehistory.org/education/scientific-biographies/howard-walter-florey-and-ernst-boris-chain
pbs.org/newshour/health/the-real-story-behind-the-worlds-first-antibiotic
Ramon y Cajal biography history.nih.gov/pages/viewpage.action?pageId=1016727
Florey letters royalsocietypublishing.org/doi/pdf/10.1098/rsbm.1971.0011
Republication of 1940 Penicillin as Chemotherapeutic Agent journals.lww.com/clinorthop/fulltext/2005/10000/the_classic__penicillin_as_a_chemotherapeutic.7.aspx
Howard Florey and the Development of Penicillin jstor.org/stable/pdf/532209
History of Corn! washingtonpost.com/news/wonk/wp/2012/08/16/a-brief-history-of-u-s-corn-in-one-chart
Anne Miller and the New Haven hospital https://medicine.yale.edu/news/yale-medicine-magazine/article/fulton-penicillin-and-chance/
nytimes.com/1999/06/09/us/anne-miller-90-first-patient-who-was-saved-by-penicillin.html
Younkin’s economic model (2008) https://irle.berkeley.edu/culture/papers/Younkin-Mar08.pdf
💻 C O N T A C T 💻
If you’d like to sponsor a video or have other business inquiries:
patkellyteaches [at] gmail.com
⌛T I M E S T A M P S ⌛
0:00 intro
0:37 Alexander Fleming and St. Mary’s4
4:27 Penicillin pharmacology
8:37 The Oxford Crew
12:44 1939 Mouse Experiment
16:14 Penicillin Production
24:47 The Economics of Penicillin
27:37 The Problems with Penicillin
#historyofmedicine #medicalhistory
Penicillin's discovery by Alexander Fleming in 1929 gets a lot of hype as the advent of antibiotics. But in reality, Fleming was just one part of the story. A team from Oxford University led by Howard Florey, in partnership with the Northern Lab in the USA brought penicillin production to the world. In this video, Patrick Kelly tells the history of penicillin.
☠️NONE OF THE INFORMATION IN THIS VIDEO SHOULD BE USED AS MEDICAL ADVICE OR OPINION. IT IS FOR GENERAL EDUCATION AND ENTERTAINMENT☠️
🔗 L I N K S 🔗
📱Instagram: instagram.com/patkellyteaches
🐦Twitter: twitter.com/PatKellyTeaches
💰Patreon: patreon.com/corporis
🔬Main channel: youtube.com/corporis
📚My favorite books docs.google.com/document/d/1wuG-8EiF2lMbFdEG-9k1qi1d1KZAdGK1o41o7SYed_k/edit?usp=sharing
🔑 P A T R O N S 🔑
Ron Blumenfeld
Joanne K
Sal F.
Ansel K
Anton
Brandon K
Rourou Y
Brendan P
Dane M
Kristoffer R
Jakub V
Joe B
Karly N
Mindi F
Kathy K
Hyeon-Seo
Jacob S.
Robin B
Sarah B
Carl
Karen S
Michael R
Brian H
Brian T
Waffles the Dog
Silverstar
Robb W
Brian B
Michael G
📜 S O U R C E S 📜
Image attributions and fact checked script can be found here. You do not need to be a Patron to view: patreon.com/posts/penicillin-89784054
Miracle Cure, the Creation of Antibiotics amazon.com/Miracle-Cure-Creation-Antibiotics-Medicine/dp/0525428100?&_encoding=UTF8&tag=corporis-20&linkCode=ur2&linkId=536c2608b02b02e77356edd136b4d016&camp=1789&creative=9325
Science, Government, and the Mass Production of Penicillin by PETER NEUSHUL (1993)
jstor.org/stable/24623264
The Discovery of Penicillin: New Insights After More Than 75 Years of Clinical Use (2017) ncbi.nlm.nih.gov/pmc/articles/PMC5403050
Post- penicillin antibiotics researchgate.net/publication/32886496_Post_penicillin_antibiotics_from_acceptance_to_resistance
Fleming biographies
aai.org/About/History/Notable-Members/Nobel-Laureates/AlexanderFleming
sciencehistory.org/education/scientific-biographies/alexander-fleming
pbs.org/wgbh/aso/databank/entries/bmflem.html
scientificamerican.com/article/penicillin-wasn-rsquo-t-alexander-fleming-rsquo-s-first-major-discovery
ncbi.nlm.nih.gov/pmc/articles/PMC4520913
Fleming’s 1917 Flavine paper
thelancet.com/journals/lancet/article/PIIS0140-6736(01)52126-1/fulltext
Fleming’s WW1 notebook clippings
bl.uk/collection-items/alexander-flemings-notebook-june-1917-1918
Fleming’s 1929 Penicillin paper
ncbi.nlm.nih.gov/pmc/articles/PMC2048009/pdf/brjexppathol00255-0037.pdf
Fleming’s 1932 Lysozyme retrospective in Journal of Royal Society of Medicine
journals.sagepub.com/toc/jrsa/26/2
Fleming BMJ 1941 correspondence
ncbi.nlm.nih.gov/pmc/articles/PMC2162878/pdf/brmedj04059-0024a.pdf
Did Fleming deserve the Nobel? link.springer.com/content/pdf/10.1007/s11948-019-00149-5.pdf
Beta-lactam pharmcology
ncbi.nlm.nih.gov/pmc/articles/PMC5369031
ncbi.nlm.nih.gov/books/NBK554560
sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/beta-lactam-antibiotic
pubs.acs.org/doi/10.1021/ja038445l
ncbi.nlm.nih.gov/pmc/articles/PMC7144564
Florey and Chain biography sciencehistory.org/education/scientific-biographies/howard-walter-florey-and-ernst-boris-chain
pbs.org/newshour/health/the-real-story-behind-the-worlds-first-antibiotic
Ramon y Cajal biography history.nih.gov/pages/viewpage.action?pageId=1016727
Florey letters royalsocietypublishing.org/doi/pdf/10.1098/rsbm.1971.0011
Republication of 1940 Penicillin as Chemotherapeutic Agent journals.lww.com/clinorthop/fulltext/2005/10000/the_classic__penicillin_as_a_chemotherapeutic.7.aspx
Howard Florey and the Development of Penicillin jstor.org/stable/pdf/532209
History of Corn! washingtonpost.com/news/wonk/wp/2012/08/16/a-brief-history-of-u-s-corn-in-one-chart
Anne Miller and the New Haven hospital https://medicine.yale.edu/news/yale-medicine-magazine/article/fulton-penicillin-and-chance/
nytimes.com/1999/06/09/us/anne-miller-90-first-patient-who-was-saved-by-penicillin.html
Younkin’s economic model (2008) https://irle.berkeley.edu/culture/papers/Younkin-Mar08.pdf
💻 C O N T A C T 💻
If you’d like to sponsor a video or have other business inquiries:
patkellyteaches [at] gmail.com
⌛T I M E S T A M P S ⌛
0:00 intro
0:37 Alexander Fleming and St. Mary’s4
4:27 Penicillin pharmacology
8:37 The Oxford Crew
12:44 1939 Mouse Experiment
16:14 Penicillin Production
24:47 The Economics of Penicillin
27:37 The Problems with Penicillin
#historyofmedicine #medicalhistory
