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RCSBProteinDataBank | Penicillin Binding Protein: Crosslinking peptidoglycan chains @RCSBProteinDataBank | Uploaded February 2018 | Updated October 2024, 4 days ago.
Full story at pdb101.rcsb.org/learn/videos/staphylococcus-aureus-and-antibiotic-resistance

In this video you can see how the D-alanyl-D-alanine peptidase domain of Penicillin Binding Protein creates a crosslink between two chains in the peptidoglycan.

This video was created as a learning resource for the 2018 RCSB PDB Video Challenge for High School Students "Mechanisms of Bacterial Resistance to Beta-lactam Antibiotics".

To find out more about the challenge and to participate visit PDB-101 (pdb101.rcsb.org/events/video-challenge/the-challenge).
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Penicillin Binding Protein: Crosslinking peptidoglycan chains @RCSBProteinDataBank

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