Uploaded June 2026 | Updated September 2026, 3 weeks ago
Dave Asprey welcomes Dr. John Gildea and David Roberts for a deep conversation on microplastics, detox pathways, sulforaphane, NRF2, glutathione, BPA, hormone disruption, brain aging, and the hidden toxins that may be affecting your energy, fertility, metabolism, and long-term health.
This episode breaks down how microplastics in the body may build up inside cells, why your lysosomes act like cellular garbage disposals, and how the body may use phase-two detox systems like glutathione, glucuronidation, and sulfation to move toxins out.
The conversation also explores estrogen detox, berberine, AMPK, SIRT1, BDNF, vivid dreams, autism, ADHD, weight loss toxins, and why losing fat too fast may release stored chemicals back into circulation.
Connect with Dave Asprey!
Website: daveasprey.com
TikTok: tiktok.com/@daveaspreyofficial
Instagram: instagram.com/dave.asprey
Facebook: facebook.com/Daveaspreyofficial
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YouTube: youtube.com/c/daveaspreybpr
The Human Upgrade Podcast: instagram.com/TheHumanUpgradePodcast https://m.facebook.com/Thehumanupgrade
Danger Coffee: dangercoffee.com/DAVE15
Dave Asprey’s BEYOND Conference: beyondconference.com
Dave Asprey’s New Book - Heavily Meditated: daveasprey.com/heavily-meditated
Dave's favorite supplements: shopsuppgradelabs.com/discount/DAVE15
Join my Substack: substack.daveasprey.com
Upgrade Labs: upgradelabs.com
40 Years of Zen: 40yearsofzen.com
Dave Asprey welcomes Dr. John Gildea and David Roberts for a deep conversation on microplastics, detox pathways, sulforaphane, NRF2, glutathione, BPA, hormone disruption, brain aging, and the hidden toxins that may be affecting your energy, fertility, metabolism, and long-term health.
This episode breaks down how microplastics in the body may build up inside cells, why your lysosomes act like cellular garbage disposals, and how the body may use phase-two detox systems like glutathione, glucuronidation, and sulfation to move toxins out.
The conversation also explores estrogen detox, berberine, AMPK, SIRT1, BDNF, vivid dreams, autism, ADHD, weight loss toxins, and why losing fat too fast may release stored chemicals back into circulation.
Connect with Dave Asprey!
Website: daveasprey.com
TikTok: tiktok.com/@daveaspreyofficial
Instagram: instagram.com/dave.asprey
Facebook: facebook.com/Daveaspreyofficial
X: https://x.com/daveasprey
YouTube: youtube.com/c/daveaspreybpr
The Human Upgrade Podcast: instagram.com/TheHumanUpgradePodcast https://m.facebook.com/Thehumanupgrade
Danger Coffee: dangercoffee.com/DAVE15
Dave Asprey’s BEYOND Conference: beyondconference.com
Dave Asprey’s New Book - Heavily Meditated: daveasprey.com/heavily-meditated
Dave's favorite supplements: shopsuppgradelabs.com/discount/DAVE15
Join my Substack: substack.daveasprey.com
Upgrade Labs: upgradelabs.com
40 Years of Zen: 40yearsofzen.com
