How Roundup Kills Weeds (And How Weeds are Fighting Back) @ACSReactions
How Roundup Kills Weeds (And How Weeds are Fighting Back)  @ACSReactions
Uploaded September 2022 | Updated September 2026, 2 weeks ago
In 1997 there were 432 new patents for herbicides, by 2009 there were only 65. The development of broad spectrum glyphosate and “Roundup Ready crops” was a game changer that worked so well people basically stopped looking for new herbicides. That is until the weeds started fighting back.

Chemical & Engineering News article on the search for new modes of action
cen.acs.org/environment/pesticides/crop-protection-herbicide-mode-action-glyphosate/100/i22

Introduction to the Shikimate Pathway
youtube.com/watch?v=FlBrJW-qbXA&list=PL833687AEAAE90961&index=155


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Executive Producer:
Matthew Radcliff

Producers:
Elaine Seward
Andrew Sobey
Darren Weaver

Host:
Alex Dainis

Scientific Consultants:
Mark Loux, PhD
Patrick J. Tranel, PhD
Todd Gaines, PhD
Mithila Jugulam, Ph.D.
Leila Duman, PhD
Brianne Raccor, PhD

Executive in Charge for PBS: Maribel Lopez
Director of Programming for PBS: Gabrielle Ewing
Assistant Director of Programming for PBS: John Campbell


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Additional Sources:
Molecular basis for the herbicide resistance of Roundup Ready crops
ncbi.nlm.nih.gov/pmc/articles/PMC1559744

THE SHIKIMATE PATHWAY
annualreviews.org/doi/10.1146/annurev.arplant.50.1.473

Why have no new herbicide modes of action appeared in recent years?
onlinelibrary.wiley.com/doi/10.1002/ps.2333

The Pitfalls of Relating Weeds, Herbicide Use, and Crop Yield: Don't Fall Into the Trap! A Critical Review
frontiersin.org/articles/10.3389/fagro.2020.615470/full

The cost of herbicide resistance
https://crops.extension.iastate.edu/blog/bob-hartzler/cost-herbicide-resistance

Development and Characterization of a CP4 EPSPS-Based, Glyphosate-Tolerant Corn Event
web.archive.org/web/20090319094255/http://crop.scijournals.org/cgi/content/abstract/45/1/329?ijkey=44fad6f377d5b5dfe274484eb51a4c79d0d7ff63&keytype2=tf_ipsecsha

Tyrosine Biosynthesis, Metabolism, and Catabolism in Plants
bit.ly/3CsMiiS

Biosynthesis and Metabolic Fate of Phenylalanine in Conifers
ncbi.nlm.nih.gov/pmc/articles/PMC4942462

Auxin driven indoleamine biosynthesis and the role of tryptophan as an inductive signal in Hypericum perforatum (L.)
ncbi.nlm.nih.gov/pmc/articles/PMC6797091

Finding of No Significant Impact
Animal and Plant Health Inspection Service
Petition for Non-regulated Status for Soybean Line MON 89788 (APHIS 06-178-01p)
aphis.usda.gov/brs/aphisdocs/06_17801p_ea.pdf

Glyphosate resistance: state of knowledge
onlinelibrary.wiley.com/doi/pdf/10.1002/ps.3743
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How Roundup Kills Weeds (And How Weeds are Fighting Back)

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