Eschenmoser-Tanabe Fragmentation Mechanism | Organic Chemistry @OrganicMechanismsChannel

Uploaded March 2023 | Updated September 2026, 1 week ago

The mechanism for a Eschenmoser-Tanabe fragmentation reaction which involves the fragmentation of α,β-epoxyketones via the intermediacy of α,β-epoxy sulfonyl hydrazones. This reaction has can be employed to synthesize strained alkynes which have the potential to be used for click chemistry

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