Fiesselmann Thiophene Synthesis Mechanism | Organic Chemistry @OrganicMechanismsChannel

Uploaded August 2023 | Updated September 2026, 1 week ago

The mechanism for a Fiesselmann thiophene synthesis reaction which involves the condensation reaction of thioglycolic acid derivatives with acetylenic esters, which upon treatment with base results in the formation of 3-hydroxy-2-thiophenecarboxylic acid derivatives.

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