Does TMAO *cause* Heart Disease? | Kevin Klatt PhD RD  @NutritionMadeSimple
Does TMAO *cause* Heart Disease? | Kevin Klatt PhD RD  @NutritionMadeSimple
Nutrition Made Simple! | Does TMAO *cause* Heart Disease? | Kevin Klatt PhD RD @NutritionMadeSimple | Uploaded June 2024 | Updated October 2024, 6 hours ago.
Is TMAO a cause of heart disease or an innocent bystander? What is TMAO and what foods raise it? Should we avoid foods high in TMAO (or foods that raise TMAO levels)?

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References:
TMAO production from choline & carnitine:
mdpi.com/2072-6643/12/5/1330

TMAO & risk of disease:
link.springer.com/article/10.1007/s11883-021-00910-x
ncbi.nlm.nih.gov/pmc/articles/PMC7975634

TMAO genetics (mendelian randomization):
sciencedirect.com/science/article/pii/S2161831323014515
mdpi.com/1422-0067/24/3/1940

What fraction of TMAO level is explained by diet?
onlinelibrary.wiley.com/doi/abs/10.1002/mnfr.201700363

TMAO & microbiome:
nature.com/articles/nm.3145.

TMAO, whole grains and fish:
sciencedirect.com/science/article/pii/S0002916522004634

Disclaimer: The contents of this video are for informational purposes only and are not intended to be medical advice, diagnosis, or treatment, nor to replace medical care. The information presented herein is accurate and conforms to the available scientific evidence to the best of the author's knowledge as of the time of posting. Always seek the advice of your physician or other qualified health provider with any questions regarding any medical condition. Never disregard professional medical advice or delay seeking it because of information contained in Nutrition Made Simple!.

#NutritionMadeSimple #GilCarvalho

0:00 What is TMAO?
1:35 Cause or innocent bystander?
3:22 Randomized trials
4:16 Genetics
5:37 TMAO levels
7:14 Observational studies
10:37 Diet vs endogenous production
12:04 Whole grains and fish
15:42 Individual nutrients
19:25 Small effects
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Does TMAO *cause* Heart Disease? | Kevin Klatt PhD RD @NutritionMadeSimple

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