Differential Diagnosis and Workup of Thoracic Aortic Aneurysm @MayoClinic
Differential Diagnosis and Workup of Thoracic Aortic Aneurysm  @MayoClinic
Uploaded June 2026 | Updated September 2026, 3 weeks ago
Guest: Juan M. Bowen, M.D.
Host: Malcolm R. Bell, M.D.

Thoracic aortic aneurysms are often found as incidental findings on imaging done for other indications. In this episode, listeners will learn more about the approach the Mayo Clinic Marfan and Thoracic Aorta Clinic takes. We can often find the cause by taking a directed family history and personal history, by looking for key physical findings, and by obtaining appropriate imaging and often also genetic tests.

Topics Discussed:
• What is the differential diagnosis in adult patients?
• What questions are most helpful in the patient history, and what physical findings should the examiner look for?
• What cardiac and vascular imaging should be done on the initial evaluation?
• When should genetic tests be considered?
• When should preventive aortic repair be considered?

0:00 Introduction to Thoracic Aortic Disease
1:03 Defining Thoracic Aortic Aneurysm
2:27 Differential Diagnosis and Referral Patterns
3:35 Genetic and Acquired Causes
5:35 Key History and Exam Findings
7:27 Preferred Imaging Approach
8:49 Head-to-Pelvis Imaging Considerations
9:29 Genetic Testing and Precision Medicine
11:21 Follow-Up Imaging and Surveillance
12:12 Closing Thoughts and Future Episodes
12:42 Cardiovascular Education Resources
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Differential Diagnosis and Workup of Thoracic Aortic Aneurysm

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