From Joint Damage to Regeneration | Tomorrows Cure Season 5 Episode 5 @MayoClinic
From Joint Damage to Regeneration | Tomorrows Cure Season 5 Episode 5  @MayoClinic
Uploaded July 2026 | Updated September 2026, 3 weeks ago
What if repairing damaged cartilage could be done in a single procedure? Using your own cells and the healing signals they need to recover?

In this episode of Tomorrow's Cure, host Lindsey Seavert explores RECLAIM, an innovative regenerative medicine approach that combines a patient's own cartilage cells with donor medicinal signaling cells (MSCs) to help repair damaged joints. Joining the conversation are Dr. Daniel Saris and Dr. Mario Hevesi of Mayo Clinic, along with Dr. Christian Lattermann of Mass General Brigham.

Together, they discuss why cartilage injuries are so difficult to treat, how RECLAIM works, and why this breakthrough could reshape the future of orthopedic surgery, sports medicine, and joint preservation.

Subscribe to Tomorrow’s Cure for conversations with the experts advancing the future of medicine, one breakthrough at a time.

This podcast is for informational purposes only and should not be relied upon as professional, medical or legal advice. Always consult with a qualified health care provider for any medical advice. The appearance of any guest does not imply an endorsement of them, their employer, or any entity they represent. The views and opinions are those of the speakers and do not necessarily reflect the views of Mayo Clinic. Reference to any product, service or entity does not constitute an endorsement or recommendation by Mayo Clinic.

0:00 RECLAIM Advances Cartilage Repair
1:45 Why Damaged Cartilage Struggles to Heal
4:13 How RECLAIM Supports Joint Surgery
7:01 Recovery Time and Patient Experience
8:22 Treating the Entire Joint System
10:03 How RECLAIM Recycles Cartilage Cells
12:43 How Donor Cells Guide Healing
15:18 Expanding Treatment From Knees to Hips
18:05 New Uses Beyond Cartilage Repair
24:22 Patient Outcomes and Clinical Trial Results
27:28 AI, Precision Treatment and Future Access
32:09 Who May Be a RECLAIM Candidate
32:32 What Gives Researchers Hope
34:52 Aging, Cell Health and Joint Repair
38:20 Delaying Joint Replacement Through Preservation
39:25 Future Insights From RECLAIM Research
39:39 Closing Remarks and Podcast Credits

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From Joint Damage to Regeneration | Tomorrow's Cure Season 5 Episode 5

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