Diazo Synthesis (IOC 48) @ThatChemistOld
Diazo Synthesis (IOC 48)  @ThatChemistOld
Uploaded May 2022 | Updated September 2026, 1 week ago
In this episode, I discuss the synthesis of diazo compounds using diazo transfer, from hydrazones, as well as through diazotization!

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Links to articles discussed in this episode:

practice problem 1 - doi.org/10.1016/S0040-4039(98)01465-8
practice problem 2 - doi.org/10.1021/jo00302a027
practice problem 3 - doi.org/10.1016/S0040-4039(01)02368-1
diazo review - doi.org/10.1021/acs.chemrev.5b00121
1st diazo transfer - doi.org/10.1016/j.tetlet.2014.03.115
2nd diazo transfer - doi.org/10.1055/s-0039-1690905
3rd diazo transfer - doi.org/10.1016/j.tet.2014.05.054
4th diazo transfer - doi.org/10.1055/s-0036-1588174
1st hydrazone - doi.org/10.3762/BJOC.17.47
2nd hydrazone - doi.org/10.1016/j.tetlet.2011.01.116
3rd hydrazone - doi.org/10.1016/j.tetlet.2020.152267
4th hydrazone - doi.org/10.1021/acscatal.1c00264
1st diazotization - doi.org/10.1016/j.tet.2012.03.022
2nd diazotization - doi.org/10.1016/S0960-894X(02)00241-X
3rd diazotization - doi.org/10.1016/j.jfluchem.2021.109899
4th diazotization - doi.org/10.1016/j.tetlet.2009.03.118
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Diazo Synthesis (IOC 48)

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