Uploaded April 2022 | Updated September 2026, 1 week ago

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In this episode, I discuss the specific methods for selectively reducing alkenes, alkynes, as well as the general approaches for hydrogenation. I discuss P-2, Lindlar's catalyst, Stryker's Reagent, diimide, and other catalysts!

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Links to articles discussed in this episode:
platinum hydrogenation - doi.org/10.1016/S0040-4020(01)82913-6
palladium hydrogenation - doi.org/10.1021/ol061147j
Lindlar reduction - doi.org/10.1021/ol4024634
P-2 reduction - doi.org/10.1002/jccs.200000004
first metal reduction - doi.org/10.1021/jm0002533
second metal reduction - doi.org/10.1021/ja005644l
diimide reduction - doi.org/10.1002/047084289X.rd235
diimide reduction example - doi.org/10.1002/0471264180.or040.02
Stryker reduction - doi.org/10.1021/ja00209a048
Hantzsch reduction - doi.org/10.1002/047084289X.rn01318.pub2
Stryker reduction example - doi.org/10.1021/ja00209a048
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I hope you enjoyed the video! I'm planning on making a full series of videos if these videos are helpful for people!

Recommended Texts:
J. Clayden, N. Greeves, S. Warren, Organic Chemistry Second Edition, Oxford University Press, 2012. (especially good for mechanism and physical chemistry explanations)
T. W. G. Solomons, C. B. Fryle, S. A. Snyder, Organic Chemistry Twelfth Edition, Wiley-VCH Verlag GmbH & Co. KGaA, 2016.
LibreTexts:
chem.libretexts.org/Bookshelves/Organic_Chemistry