Modern Healthspan | Demystifying NAD Precursors & SARM1 In The Brain | Dr Lindsay Wu Ep2 @ModernHealthspan | Uploaded November 2023 | Updated October 2024, 1 hour ago.
Here Dr Wu talks about how NMN and NR impact SARM1, which is an enzyme in the brain which causes axonal degeneration and death. According to Dr Wu this is only in cases of damage to the neuron and normally NMN would not accumulate in the cell.
Some links are affiliate links so we will earn a commission when they are used to purchase products.
*Renue By Science* 10% : Code MHS Use SUBMHS for 15% on subscription orders
NMN tinyurl.com/3wr8pr3t
*ProHealth* 15% discount Code MODERN : prohealth.pxf.io/Gm1mKk
NMN Pro 1000 prohealth.pxf.io/Jz4dL2
*DoNotAge* 10% discount code MHS tinyurl.com/6dbvhv87
NMN tinyurl.com/wyzj2f3d
Nuchido Time+ 20% discount of first purchase with code MODERN20 nuchido.com/MODERN
NOVOS Core & Boost novos.sjv.io/daqJ0Q code 5OFFMHS
☕If you would like to support our channel, we’d love a coffee…thank you! _buymeacoffee.com/mhealthspan_
*Insidetracker* 20% discount Code MODERN20 _insidetracker.sjv.io/NkbP7V_
*Bulletproof* 15% off with coupon code: HEALTHSPAN15: _tinyurl.com/4npjk5vp_
*SiPhox Health* 20 % Code MODERN blood test (only in US & Canada) _siphoxhealth.com/discount/modern_
*Delavie Sciences* 10% Code Modern Age Defying Serum tinyurl.com/yp2jmhy8 Eye Refresh tinyurl.com/mt8knv3s
*OmegaQuant* 5% discount Code MODERN _omegaquant.com/shop/_
⏲️Chapters
00:00 What is SARM1
01:40 Why does NMN accumulate
02:36 SARM1 action
03:26 Compared to NR
04:26 Blocking SARM1
Dr Lindsay Wu is an NHMRC Research Fellow and is the Head of the Laboratory for Ageing Research at UNSW Sydney. He has a background in molecular biology, biochemistry and drug development.
Dr Wu received his PhD at the Garvin Institute of Medical Research after studying at the University of Sydney.
🌐Links in this video
Host–microbiome interactions in nicotinamide mononucleotide (NMN) deamidation
febs.onlinelibrary.wiley.com/doi/10.1002/1873-3468.14698
Dr Wu's page at UNSW https://www.unsw.edu.au/staff/lindsay-wu
***************************************
Health claims Disclosure: Information provided on this video is not a substitute for direct, individual medical treatment or advice. Please consult with your doctor first. Products or services mentioned in this video are not a recommendation.
Audio Copyright Disclaimer
Please note that we have full authorization to the music that we used in our videos as they were created using the service WeVideo which provides the rights to the music. The rights are detailed in the terms of use that can be reviewed here wevideo.com/terms-of-use and any following inquiries should be addressed to legal@wevideo.com.
**************************************************
📖Books
*Dr Peter Attia*
Outlive: The Science and Art of Longevity - _amzn.to/472lu68_
*Dr David Sinclair*
Lifespan Book – _amzn.to/2MESFVb_
*Dr Sandra Kaufmann*
The Kaufmann Protocol: Aging Solutions _amzn.to/3Typ41x_
The Kaufmann Protocol: Why we Age and How to Stop it _amzn.to/3yWnEEo_
*Dr Steven Gundry* -
Unlocking the Keto Code - _amzn.to/3ID7pi4_
The Longevity Paradox - _amzn.to/3q7t2nC_
The Plant Paradox - _amzn.to/3Q9E32j_
*Dr Mary Newport*
Clearly Keto: For Healthy Brain Aging and Alzheimer’s Prevention _amzn.to/3XRhKih_
The Complete Book of Ketones: A Practical Guide to Ketogenic Diets and Ketone Supplements _amzn.to/4008cmX_
#NAD #NMN #nr
Here Dr Wu talks about how NMN and NR impact SARM1, which is an enzyme in the brain which causes axonal degeneration and death. According to Dr Wu this is only in cases of damage to the neuron and normally NMN would not accumulate in the cell.
Some links are affiliate links so we will earn a commission when they are used to purchase products.
*Renue By Science* 10% : Code MHS Use SUBMHS for 15% on subscription orders
NMN tinyurl.com/3wr8pr3t
*ProHealth* 15% discount Code MODERN : prohealth.pxf.io/Gm1mKk
NMN Pro 1000 prohealth.pxf.io/Jz4dL2
*DoNotAge* 10% discount code MHS tinyurl.com/6dbvhv87
NMN tinyurl.com/wyzj2f3d
Nuchido Time+ 20% discount of first purchase with code MODERN20 nuchido.com/MODERN
NOVOS Core & Boost novos.sjv.io/daqJ0Q code 5OFFMHS
☕If you would like to support our channel, we’d love a coffee…thank you! _buymeacoffee.com/mhealthspan_
*Insidetracker* 20% discount Code MODERN20 _insidetracker.sjv.io/NkbP7V_
*Bulletproof* 15% off with coupon code: HEALTHSPAN15: _tinyurl.com/4npjk5vp_
*SiPhox Health* 20 % Code MODERN blood test (only in US & Canada) _siphoxhealth.com/discount/modern_
*Delavie Sciences* 10% Code Modern Age Defying Serum tinyurl.com/yp2jmhy8 Eye Refresh tinyurl.com/mt8knv3s
*OmegaQuant* 5% discount Code MODERN _omegaquant.com/shop/_
⏲️Chapters
00:00 What is SARM1
01:40 Why does NMN accumulate
02:36 SARM1 action
03:26 Compared to NR
04:26 Blocking SARM1
Dr Lindsay Wu is an NHMRC Research Fellow and is the Head of the Laboratory for Ageing Research at UNSW Sydney. He has a background in molecular biology, biochemistry and drug development.
Dr Wu received his PhD at the Garvin Institute of Medical Research after studying at the University of Sydney.
🌐Links in this video
Host–microbiome interactions in nicotinamide mononucleotide (NMN) deamidation
febs.onlinelibrary.wiley.com/doi/10.1002/1873-3468.14698
Dr Wu's page at UNSW https://www.unsw.edu.au/staff/lindsay-wu
***************************************
Health claims Disclosure: Information provided on this video is not a substitute for direct, individual medical treatment or advice. Please consult with your doctor first. Products or services mentioned in this video are not a recommendation.
Audio Copyright Disclaimer
Please note that we have full authorization to the music that we used in our videos as they were created using the service WeVideo which provides the rights to the music. The rights are detailed in the terms of use that can be reviewed here wevideo.com/terms-of-use and any following inquiries should be addressed to legal@wevideo.com.
**************************************************
📖Books
*Dr Peter Attia*
Outlive: The Science and Art of Longevity - _amzn.to/472lu68_
*Dr David Sinclair*
Lifespan Book – _amzn.to/2MESFVb_
*Dr Sandra Kaufmann*
The Kaufmann Protocol: Aging Solutions _amzn.to/3Typ41x_
The Kaufmann Protocol: Why we Age and How to Stop it _amzn.to/3yWnEEo_
*Dr Steven Gundry* -
Unlocking the Keto Code - _amzn.to/3ID7pi4_
The Longevity Paradox - _amzn.to/3q7t2nC_
The Plant Paradox - _amzn.to/3Q9E32j_
*Dr Mary Newport*
Clearly Keto: For Healthy Brain Aging and Alzheimer’s Prevention _amzn.to/3XRhKih_
The Complete Book of Ketones: A Practical Guide to Ketogenic Diets and Ketone Supplements _amzn.to/4008cmX_
#NAD #NMN #nr
